Pediatric Liver Tumors

Prof.Dr.med.em Arthur Zimmermann graduated in Medicine at the University of Berne, Switzerland. He attended the local Pathology Residency Program, followed by several years of experipmental basic research in the fields of cancer cell cycle mutants and mechanisms of leukocyte and cancer cell motility. As chief of staff and then head of the division of surgical pathology at the University of Berne he specialized in hepatobiliary and pancreatic tumor pathology, where he became the author and coauthor of more than 500 publications. Until July 2009, Prof. Zimmermann was Acting Director of the Institute of Pathology of the University of Berne. As an expert in pediatric liver tumors he is an international consultant and holds the Pathology Review Center for the International Childhood Liver Tumor Study Group ( SIOPEL ). Prof. Giorgio Perilongo graduated in Medicine in 1980 at the University of Padua, Italy; he then attended the local Pediatric Residency program for then completing his post-graduate education with a fellowship in Hematology-Oncology first and in Neuro-Oncology thereafter at the Children’s Hospital of Philadelphia. Presently he is the Chairman of the Department of Pediatrics of the University Hospital in Padua. He was among the founders of the International Childhood Liver Tumor Study Groups (otherwise known as SIOPEL group), the international cooperative research group on childhood liver tumors based in Europe conceived within the umbrella of the International Society of Pediatric Oncology. Within this group is has and he is still playing a very active role. He chaired a series of clinical trials already published in the main international scientific journals.

From the reviews: "This slender but tightly packed book is essentially a report on the current status of surgical and chemotherapeutic treatment of childhood liver tumors, based on the most current data from the American and European collaborative treatment groups. ... Pediatric surgeons working in specialized tumor surgery settings, with the Children's Oncology Group, or who support research activities in liver tumors will find this book invaluable. ... It will stand as a thorough and quick reference in the topic as currently understood, diagnosed, and treated." (Robert M. Arensman, Doody's Review Services, September, 2011)

• Part 1 Basic: Epidemiology.-Etiology/Molecular Biology,-Embryology/ontogenic aspects of liver carcinogenesis.Part 2 Diagnosis: Clinical presentation.-Imaging.-Pathology.Part 3 Therapy: Surgery.-Transplantation.-Chemotherapy.-Salvage strategies.-Alternative approaches.-Supportive therapy and toxicity.-Design and analysis of trials.Part 4 Other rare hepatic tumors in infancy and childhood