Dynamics in Enzyme Catalysis

AvJudith Klinman,Sharon Hammes- Schiffer

Inbunden, Engelska, 2013

Del i serien Topics in Current Chemistry

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Beskrivning

Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase.

Produktinformation

Utgivningsdatum:2013-08-08
Mått:155 x 235 x 18 mm
Vikt:472 g
Format:Inbunden
Språk:Engelska
Serie:Topics in Current Chemistry
Antal sidor:212
Upplaga:2013
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783642389610

Utforska kategorier

Fysikalisk kemi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

Innehållsförteckning

Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer.- Protein Conformational Disorder and Enzyme Catalysis.- A Surprising Role for Conformational Entropy in Protein Function.- Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations.- Structured Crowding and Its Effects on Enzyme Catalysis.- Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations.- Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase.- Protein Dynamics and the Enzymatic Reaction Coordinate.