Document from the year 2016 in the subject Computer Science - Bioinformatics, , language: English, abstract: Why is it so important for bioinformatics to get alignments? Where are the problems and how can they be solved?This manuscript gives a short overview about some of the methods to analyse sequences as well as the Needleman- Wunsch and the Smith-Waterman Algorithm. You can get an Overview how to interpret a Dotplot. Also you can learn how to create global and local alignments.