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Beskrivning
This volume provides an update on the use of molecular biology of the lung and their diseases. The text applies to the basic mechanisms of cell biology, receptors and cell activation, as well as providing an insight as to how the technology influences the concepts of pathogenesis and vice-versa.
Application of transgenic and gene-targeted mice to dissect mechanisms of lung disease, Steven D. Shapiro. Emphysema: models of genetic emphysema - the C57B1/6J mice and their mutants - tight-skin, pallid and biege, Guiseppe Lungarella et al; x1-antitrypsin deficiency, R.A. Stockley; recombinant SLPI - emphysema and asthma, J. Stolk and P.S. Hiemstra; elastase inhibitors in the lung - expression and functional relationships, Jean-Michael Sallenave et al; regulation of neutrophil proteases, Anne B. Sturrock and John R. Hoidal; control of connective tissue genes, Joel Rosenbloom. Infection: genetic models of bacterial lung infection, Timothy J. Mitchell; genetics of bacteria - role in pathogenesis of infection of the respiratory tract infections, Neil W. Schluger; cystic fibrosis, Uta Griesenbach et al; respiratory bacterial infections in patients with cystic fibrosis - pathogenicity and implications for serine proteinase inhibitor therapy, Gerd Doring.
