This volume covers a range of topics including caco-2 cell permeability versus human gastrointestinal absorption - QSPR analysis; pharmacology of appetite supression; serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors; neuropeptides in drug research; regulation of NMDA receptors by ethanol; and troglitazone and emerging glitazones - new avenues for potential therapeutic benefits beyond glycemic control and applications of developmental biology to medicine and agriculture.