Dementia with Lewy Bodies

Kenji Kosaka MD, PhD, Clinic Ian Center MinamiEmeritus Professor, Yokohama City University, Yokohama Japan

“The intended audience includes physicians, primarily psychiatrists, neurologists, behavioral neurologists, and neuropsychiatrists who specialize in movement disorders. … This is a superb and comprehensive book on dementia with Lewy bodies. It covers all important aspects of this degenerative disease. Any physician who diagnoses and treats patients with Lewy body disease should refer to this excellent book.” (Michael Joel Schrift, Doody’s Book Reviews, April, 2017)“The book content enables understanding of the disease since author first reported DLB in 1976, discusses not only diagnostic criteria and clinical symptoms of DLB but also various imaging modalities and biological markers, which are usefulfor diagnosis of DLB. The book is useful for psychiatrists and neurologists.” (Mirna Peco, Alcoholism and Psychiatry Research, Vol. 53 (2), 2017)

• Part I. Introduction.- 1.History and latest concept of DLB.- 2.Epidemiology of DLB.- Part II. Biological Aspects.- 3.Neuropathology of DLB.- 4.Biochemistry of DLB.- 5.Molecular biology of DLB.- Part III. Clinical Aspects.- 6.Clinical diagnostic criteria of DLB.- 7.Cognitive impairments of DLB.- 8.BPSD in DLB.- 9.Parkinson symptoms of DLB.- 10.Autonomic symptoms of DLB.- Part IV. Biological Markers.- 11.CT, MRI, SPECT and PET in DLB.- 12.DaT Scan in DLB.- 13.MIBG myocardial scintigraphy in DLB.- 14.Alpha-synuclein in cerebrospinal fluid.- 15.Electroencephalography in DLB.- 16.Ventilatory response to hypercapnia.- Part V. Treatment.- 17.Pharmacotherapy in DLB.- 18.Kampo medicine in DLB.