Pharmaceuticals, baby food, cotton clothing and cars are the four focus value chains of this report. Together they are poised to increase intraregional trade in Africa, reduce imports, diversify economies and create jobs for women and youth. The sectors were selected from 94 promising value chains and reflect African goals to improve food security, health and tech skills – making them strategic choices for governments and investors. This report offers insights to improve trade in such sectors, based on extensive data analysis and interviews with 10,000 firms, business support organizations, industry experts and other stakeholders in Africa. It recommends actions for growth and transformation across the African continent.