Aging Research in Yeast

AvMichael Breitenbach,S. Michal Jazwinski

Inbunden, Engelska, 2011

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Beskrivning

Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain).

Produktinformation

Utgivningsdatum:2011-11-19
Mått:155 x 235 x 25 mm
Vikt:735 g
Format:Inbunden
Språk:Engelska
Serie:Subcellular Biochemistry
Antal sidor:368
Upplaga:2012
Förlag:Springer
ISBN:9789400725607

Utforska kategorier

Cellbiologi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Recensioner i media

From the reviews: "This book compiles some of the most exciting and promising research to date in the fields of anti-aging, longevity, and possibly even rejuvenation. The authors' research examines the role of senescence in yeast and how it may relate to the chaotic autophagy of cancer cells. In sum, Aging Research will stir interest in both scientific and non-scientific arenas." (The Electric Review, October, 2012)

Innehållsförteckning

1. Preface and Introduction to Aging research in Yeast.- 2.Oxidative stresses and ageing.- 3.The role of Mitochondria in the aging processes of yeast.- 4.The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Aging.- 5. Chronological Aging in Saccharomyces cerevisiae.- 6. Still waters run deep: Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures.- 7. Maximising the yeast chronological lifespan.- 8.Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae.- 9. DNA damage and DNA replication stress in yeast models of aging.- 10.Yeast aging and apoptosis.-11. Cellular homeostasis in fungi: Impact on the aging process.- 12.Genome-wide analysis of yeast aging.- 13. Genetic Approaches to Aging in Budding and Fission Yeasts: New Connections and New Opportunities.- 14. Evolution of asymmetric damage segregation: a modelling approach.-15. Cellular ageing and the actin cytoskeleton.