'I would recommend its reading to haemodialysis related health care professionals, and it should be of easy access to everybody interested in the subject, including patients. As the work has been done by very prestigious professionals they have had the ability to make sometimes difficult topics easy.' EDTNA/ERCA Journal, XXIII:4 (1997) 'This is ... aimed at medical and nursing staff but one which will also be of significant value to patients. ... there is a good bibliography ... The index has been well constructed ... This is a short, clearly written, and concise text. It is well illustrated throughout and contains much useful information for patient management.' Nephrology Dialysis Transplantation, 13 (1998)

• 1. Causes and consequences of end-stage renal failure.- Epidemiology of chronic renal failure.- The uremic syndrome.- Indications for initiating dialysis therapy.- 2. Basic principles of hemodialysis.- Transport mechanisms.- Modalities of solute transport.- Evaluation of dialyzer performances.- Contribution of convection to the overall solute transport.- Assessment of solute mass removal.- 3. Blood access.- Standard arteriovenous fistula.- Alternative methods.- Complications and long-term management of arteriovenous devices.- Temporary access methods.- 4. Dialysis equipment.- Dialyzers.- Dialysis membranes.- Dialysate delivery system.- Dialysate composition.- Water treatment.- 5. Biocompatibility.- Activation of blood components.- Acute anaphylactoid reactions.- Long-term consequences of bioincompatibility.- 6. Adequacy of hemodialyis, nutrition, and dialysis prescription.- Quantification of dialysis efficacy.- Nutritional parameters of dialysis adequacy.- Choice of adequate dialysis duration.- Dietary prescription to the hemodialysis patient.- Integrated dialysis prescription.- 7. Management of the dialysis patient.- First hemodialysis session.- Monitoring of later sessions.- Technical hazards during hemodialysis sessions.- Interdialytic complications.- Modalities of hemodialysis treatment.- Long-term surveillance of the dialysis patient.- 8. Cardiovascular and neurological problems.- Hypertension.- Cardiac dysfunction in uremia.- Atherosclerosis and coronaropathy.- Pericarditis.- Valvular heart disease.- Uremic neurological involvement.- Cerebrovascular accidents.- 9. Immunologic and hematologic disorders.- Immune system dysregulation.- Bacterial infections.- Viral hepatitis.- Anemia and erythropoetin therapy.- Hemostasis disorders.- 10. Bone and joint problems.- Secondary hyperparathyroidism.- Aluminum-related osteomalacia.- Adynamic bone disease.- Beta 2-microglobulin amyloidosis.- Other osteoarticular problems.- 11. Other clinical problems.- Endocrine disorders.- Metabolic disorders.- Dermatological problems.- Gastrointestinal complications.- Complications in the diseased kidneys.- Psychological problems.- Dialysis in children.- Dialysis in the elderly.- Dialysis in the diabetic patient.- 12. Outcome and economics.- Results of maintenance hemodialysis.- Economics of dialysis therapy.- Literature for further reading.

'I would recommend its reading to haemodialysis related health care professionals, and it should be of easy access to everybody interested in the subject, including patients. As the work has been done by very prestigious professionals they have had the ability to make sometimes difficult topics easy.' EDTNA/ERCA Journal, XXIII:4 (1997) 'This is ... aimed at medical and nursing staff but one which will also be of significant value to patients. ... there is a good bibliography ... The index has been well constructed ... This is a short, clearly written, and concise text. It is well illustrated throughout and contains much useful information for patient management.' Nephrology Dialysis Transplantation, 13 (1998)

• 1. Causes and consequences of end-stage renal failure.- Epidemiology of chronic renal failure.- The uremic syndrome.- Indications for initiating dialysis therapy.- 2. Basic principles of hemodialysis.- Transport mechanisms.- Modalities of solute transport.- Evaluation of dialyzer performances.- Contribution of convection to the overall solute transport.- Assessment of solute mass removal.- 3. Blood access.- Standard arteriovenous fistula.- Alternative methods.- Complications and long-term management of arteriovenous devices.- Temporary access methods.- 4. Dialysis equipment.- Dialyzers.- Dialysis membranes.- Dialysate delivery system.- Dialysate composition.- Water treatment.- 5. Biocompatibility.- Activation of blood components.- Acute anaphylactoid reactions.- Long-term consequences of bioincompatibility.- 6. Adequacy of hemodialyis, nutrition, and dialysis prescription.- Quantification of dialysis efficacy.- Nutritional parameters of dialysis adequacy.- Choice of adequate dialysis duration.- Dietary prescription to the hemodialysis patient.- Integrated dialysis prescription.- 7. Management of the dialysis patient.- First hemodialysis session.- Monitoring of later sessions.- Technical hazards during hemodialysis sessions.- Interdialytic complications.- Modalities of hemodialysis treatment.- Long-term surveillance of the dialysis patient.- 8. Cardiovascular and neurological problems.- Hypertension.- Cardiac dysfunction in uremia.- Atherosclerosis and coronaropathy.- Pericarditis.- Valvular heart disease.- Uremic neurological involvement.- Cerebrovascular accidents.- 9. Immunologic and hematologic disorders.- Immune system dysregulation.- Bacterial infections.- Viral hepatitis.- Anemia and erythropoetin therapy.- Hemostasis disorders.- 10. Bone and joint problems.- Secondary hyperparathyroidism.- Aluminum-related osteomalacia.- Adynamic bone disease.- Beta 2-microglobulin amyloidosis.- Other osteoarticular problems.- 11. Other clinical problems.- Endocrine disorders.- Metabolic disorders.- Dermatological problems.- Gastrointestinal complications.- Complications in the diseased kidneys.- Psychological problems.- Dialysis in children.- Dialysis in the elderly.- Dialysis in the diabetic patient.- 12. Outcome and economics.- Results of maintenance hemodialysis.- Economics of dialysis therapy.- Literature for further reading.

'I would recommend its reading to haemodialysis related health care professionals, and it should be of easy access to everybody interested in the subject, including patients. As the work has been done by very prestigious professionals they have had the ability to make sometimes difficult topics easy.' EDTNA/ERCA Journal, XXIII:4 (1997) 'This is ... aimed at medical and nursing staff but one which will also be of significant value to patients. ... there is a good bibliography ... The index has been well constructed ... This is a short, clearly written, and concise text. It is well illustrated throughout and contains much useful information for patient management.' Nephrology Dialysis Transplantation, 13 (1998)

• 1. Causes and consequences of end-stage renal failure.- Epidemiology of chronic renal failure.- The uremic syndrome.- Indications for initiating dialysis therapy.- 2. Basic principles of hemodialysis.- Transport mechanisms.- Modalities of solute transport.- Evaluation of dialyzer performances.- Contribution of convection to the overall solute transport.- Assessment of solute mass removal.- 3. Blood access.- Standard arteriovenous fistula.- Alternative methods.- Complications and long-term management of arteriovenous devices.- Temporary access methods.- 4. Dialysis equipment.- Dialyzers.- Dialysis membranes.- Dialysate delivery system.- Dialysate composition.- Water treatment.- 5. Biocompatibility.- Activation of blood components.- Acute anaphylactoid reactions.- Long-term consequences of bioincompatibility.- 6. Adequacy of hemodialyis, nutrition, and dialysis prescription.- Quantification of dialysis efficacy.- Nutritional parameters of dialysis adequacy.- Choice of adequate dialysis duration.- Dietary prescription to the hemodialysis patient.- Integrated dialysis prescription.- 7. Management of the dialysis patient.- First hemodialysis session.- Monitoring of later sessions.- Technical hazards during hemodialysis sessions.- Interdialytic complications.- Modalities of hemodialysis treatment.- Long-term surveillance of the dialysis patient.- 8. Cardiovascular and neurological problems.- Hypertension.- Cardiac dysfunction in uremia.- Atherosclerosis and coronaropathy.- Pericarditis.- Valvular heart disease.- Uremic neurological involvement.- Cerebrovascular accidents.- 9. Immunologic and hematologic disorders.- Immune system dysregulation.- Bacterial infections.- Viral hepatitis.- Anemia and erythropoetin therapy.- Hemostasis disorders.- 10. Bone and joint problems.- Secondary hyperparathyroidism.- Aluminum-related osteomalacia.- Adynamic bone disease.- Beta 2-microglobulin amyloidosis.- Other osteoarticular problems.- 11. Other clinical problems.- Endocrine disorders.- Metabolic disorders.- Dermatological problems.- Gastrointestinal complications.- Complications in the diseased kidneys.- Psychological problems.- Dialysis in children.- Dialysis in the elderly.- Dialysis in the diabetic patient.- 12. Outcome and economics.- Results of maintenance hemodialysis.- Economics of dialysis therapy.- Literature for further reading.