This proceeding contains the cutting-edge research results in information science and technology, and their related technology. Recent scientific breakthroughs such as invisibility cloak and meta-materials, data mining techniques, advanced game playing in artificial intelligence, nano-technology, unlikely event probability, and fuzzy logic reasoning are just a few outstanding examples. Walter Freeman''s 80th birthday celebration is another highlight of this proceedings, because this major event is attended by many leading scientists from around the world. Key speakers include Charles Falco, Water Freeman, Thomas Huang, Meyya Meyyappan, Lotfi Zadeh, Bernette Bouchon Meunier, Heather Carlson, Ling Guan, Etienne Kerre and John Mordes.