Dr. Lobat Tayebi is the Batten Endowed Professor and Director of the Institute for Engineering in Medicine, Health, & Human Performance (EnMed) in the College of Engineering and Technology at Old Dominion University. Her research is at the interface of biology and engineering, and she has authored over 400 peer-reviewed articles as well as several issued patents and books in the field.Dr. Mohsen Abdolmaleki holds a PhD in Immunology. His research focuses on immune regulation, cancer, and inflammatory diseases. He has authored several peer-reviewed scientific publications. This book draws on his academic and research expertise in immunology.

• 1.Overview of immune system regulation.- 2. Immune checkpoint molecules: structure, function, expression.- 3. Genetics of immune checkpoints.- 4. Immune checkpoints overexpression in cancer.- 5. Cancer immunotherapy using immune checkpoint blockade.- 6. Adverse effects of immune checkpoint blockade.- 7. Autoimmune diseases.- 8. Allergy.- 9. Pregnancy.- 10. Organ transplantation.- 11. Infection: COVID-19.

Dr. Lobat Tayebi is the Batten Endowed Professor and Director of the Institute for Engineering in Medicine, Health, & Human Performance (EnMed) in the College of Engineering and Technology at Old Dominion University. Her research is at the interface of biology and engineering, and she has authored over 400 peer-reviewed articles as well as several issued patents and books in the field.Dr. Mohsen Abdolmaleki holds a PhD in Immunology. His research focuses on immune regulation, cancer, and inflammatory diseases. He has authored several peer-reviewed scientific publications. This book draws on his academic and research expertise in immunology.

• 1.Overview of immune system regulation.- 2. Immune checkpoint molecules: structure, function, expression.- 3. Genetics of immune checkpoints.- 4. Immune checkpoints overexpression in cancer.- 5. Cancer immunotherapy using immune checkpoint blockade.- 6. Adverse effects of immune checkpoint blockade.- 7. Autoimmune diseases.- 8. Allergy.- 9. Pregnancy.- 10. Organ transplantation.- 11. Infection: COVID-19.

Dr. Lobat Tayebi is the Batten Endowed Professor and Director of the Institute for Engineering in Medicine, Health, & Human Performance (EnMed) in the College of Engineering and Technology at Old Dominion University. Her research is at the interface of biology and engineering, and she has authored over 400 peer-reviewed articles as well as several issued patents and books in the field.Dr. Mohsen Abdolmaleki holds a PhD in Immunology. His research focuses on immune regulation, cancer, and inflammatory diseases. He has authored several peer-reviewed scientific publications. This book draws on his academic and research expertise in immunology.

• 1.Overview of immune system regulation.- 2. Immune checkpoint molecules: structure, function, expression.- 3. Genetics of immune checkpoints.- 4. Immune checkpoints overexpression in cancer.- 5. Cancer immunotherapy using immune checkpoint blockade.- 6. Adverse effects of immune checkpoint blockade.- 7. Autoimmune diseases.- 8. Allergy.- 9. Pregnancy.- 10. Organ transplantation.- 11. Infection: COVID-19.