This book presents peer reviewed articles from IRC-SET 2025 held on 16August in Singapore. It highlights the contemporary state of research in multi-disciplinary areas of Computer Science, Computer Engineering, Data Science, Electrical and Electronics Engineering, Chemical Engineering, Mechanical Engineering, Physics, Biomedical Sciences, Life Sciences, Medicine, Healthcare, and Business Technology. The papers presented here were shortlisted after extensive rounds of rigorous reviews by a panel of esteemed individuals who are pioneers and experts in their respective domains.