This open access book provides the uniaxial, triaxial, fatigue, creep, creep-fatigue loading tests in order to investigate the salt mechanical response and the related damage mechanisms defining relation between plastic deformation, dilatancy and damage. Based on the experimental results, a new creep-fatigue constitutive model for salt rock that considers creep-fatigue interaction was established by incorporating a state variable that characterizes rock hardening level on the basis of the Norton creep model. Different salt rock mechanical test data sets with varying stress paths were used to validate this creep-fatigue constitutive model. The fit curves and test curves of the stress paths demonstrate good consistency, indicating that the model comprehensively considers the effects of time, load, and state on salt rock's creep-fatigue, effectively describing the creep-fatigue plastic deformation features of salt rock under different stress paths.