Cytokine and Chemokine Networks in Cancer

Dr. Manzoor Ahmad Mir holds Master’s Degree in Zoology with Gold Medal from HNBG Central University and after qualifying prestigious National level CSIR-JRF-NET examination; got his Ph. D from Jawaharlal Nehru University New Delhi and CSIR-Institute of Microbial Technology Chandigarh in the field of Immunopathology. His research interest is Cancer Biology with specialization in Drug repurposing and combination therapy of breast cancer and to elucidate the molecular mechanism behind it, besides use of natural agents in treating cancer. He is also working on expression pattern and prognostic significance of chemokines/cytokines of CDKs in breast cancer besides virtual screening of drugs for cancer treatment and their mechanistic elucidation. He has published more than 50 high-impact research papers and book chapters, in recognition of which he has received several awards and Royalties from international publishing houses. Dr. Manzoor has authored more than 16 books with internationalpublishers like Elsevier USA and Nova Science Publisher USA, Bentham Sciences, IGI Global, Springer-Nature to name a few. He is on the editorial board and Reviewer of some prestigious journals and has been an invited speaker at various scientific meetings/conferences within India and abroad. He is member of many scientific organizations and societies like American Association of Cancer Research, Fellow of Royal British Society, American Association of Clinical Oncology, International Immunology Association, etc. Dr Manzoor was awarded Teachers Associate Research Excellence Fellowship (TARE) by DST Govt of India and Summer Research Fellowship Programme (SRFP-2019) by Indian Academy of Sciences and National Science Academy. Dr Manzoor has developed Massive Open Online Course (MOOCs) in Immunology, Human Genetics and Endocrinology for UG students sanctioned by UGC-Consortium for Educational Communication (CEC) SWAYAM Ministry of HRD Govt of India. He has research and teaching experience of 15 years in Cancer Biology, Animal cell and Tissue Technology, Molecular Modelling and Drug Design, Comparative Immunology. He currently teaches Cancer Biology, and Immunology at the Department of Bioresources, School of Biological Sciences, University of Kashmir. He is presently heading the Department of Bioresources, University of Kashmir.

• Chapter 1_Introduction to Cancer.- Chapter 2_Expression pattern of Chemokines in Cancer.- Chapter 3_Implications of Cytokine-Chemokine Heterogenity in Cancer.- Chapter 4_Cytokine and chemokines networks in cancer stemness.- Chapter 5_Cytokine and chemokines networks in angiogeneis.- Chapter 6_Role of Cytokine-Chemokine cascades in Epithelial to Mesenchymal Transition.- Chapter 7_Role of Chemokines in establishment of Metastatic Niche.- Chapter 8_CXCL12-CXCR4 axis in Metastasis.- Chapter 9_Chemokine and cytokine networks in the tumor microenvironment.- Chapter 10_CXCL9, CXCL10, CXCL11/CXCR3 axis and Immune Activation.- Chapter 11_CXCL8-CXCR1/2 axis in cancer and inflammatory diseases.- Chapter 12_Cytokine and Chemokine Networks in Therapeutic Resistance.- Chapter 13_Prognostic and diagnostic significance of Chemokines and cytokines in cancer.- Chapter 14_Therapeutic implications of Chemokines and cytokines networks in cancer.- Chapter 15_Chemokines in cancer therapy.​