Practical Guide to Hereditary Breast and Ovarian Cancer

Seigo NakamuraDepartment of Breast Surgical Oncology, Showa University, School of Medicine,Tokyo, JapanPresident of the Japanese Organization of Hereditary Brest and Ovarian Cancer (JOHBOC)Daisuke AokiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, JapanEditorial Director of the Japanese Organization of Hereditary Brest and Ovarian Cancer (JOHBOC)​

• Part I Breast.- 1 Establishment of a medical system with HBOC in mind.- 2 Guidelines for diagnosis and treatment of HBOC: Methods and Products.- 3 RRM from a Plastic Surgery Perspective.- Part 2 Gynecology.- 4 Significance of p53 signature in RRSO samples.- 5 Mutual feedback between gynecological HBOC practice and cancer genomic medicine.- Part 3 Basic Science.- 6 Diversity of HBOC-Related Genes Revealed by Genome Analysis.- 7 New functions of BRCA1/2 regulating carcinogenesis and drug sensitivity.- Part 4 Health and Labor Sciences Research Grant.- 8 Systemic Issues in HBOC Treatment.- 9 Current status and future issues of the activities of the relevant organizations.- Part 5 Congress Award.- 10 Understanding the significance of the test in relatives of prostate and pancreatic cancer patients who tested positive on BRACAnalysis.- 11 Handling Germline Findings in Ovarian Cancer Cases.- Part 6 JOHBOC registration.- 12 JOHBOC registration data up to date 2021.