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Two decades after the American Civil War, no name was more closely associated with the nation's inventive and entrepreneurial spirit than that of Thomas Edison. The restless changes of those years were reflected in the life of America's foremost inventor. Having cemented his reputation with his electric lighting system, Edison had decided to withdraw partially from that field. At the start of 1885, newly widowed at mid-life with three young children, he launched into a series of personal and professional migrations, setting in motion chains of events that would influence his work and fundamentally reshape his life. Edison's inventive activities took off in new directions, flowing between practical projects (such as wireless and high-capacity telegraph systems) and futuristic ones (exploring forms of electromagnetic energy and the convertibility of one to another). Inside of two years, he would travel widely, marry the daughter of a prominent industrialist and religious educator, leave New York City for a grand home in a sylvan suburb, and construct a winter laboratory and second home in Florida.Edison's family and interior life are remarkably visible at this moment; his papers include the only known diary in which he recorded personal thoughts and events. By 1887, the familiar rhythms of his life began to reassert themselves in his new settings; the family faded from view as he planned, built, and occupied a New Jersey laboratory complex befitting his status. The eighth volume of the series, New Beginnings includes 358 documents (chosen from among thousands) that are the most revealing and representative of Edison's work, life, and place in American culture in these years. Illustrated with hundreds of Edison's drawings, these documents are further illuminated by meticulous research on a wide range of sources, including the most recently digitized newspapers and journals of the day.

This richly illustrated volume explores Edison's inventive and personal pursuits from 1888 to 1889, documenting his responses to technological, organizational, and economic challenges.Thomas A. Edison was received at the 1889 Paris Exposition Universelle—the World's Fair—as a conquering hero. Extravagantly fêted and besieged by well-wishers, he was seen, like Gustave Eiffel's iron tower, as a triumphal symbol of republicanism and material progress. The visit was a high-water mark of his international fame.Out of the limelight, Edison worked as hard as ever. On top of his work as an inventor, entrepreneur, and manufacturer, he created a new role as a director of research. At his peerless laboratory in Orange, New Jersey, he directed assistants working in parallel on multiple projects. These included the "perfected" phonograph; a major but little-recognized effort to make musical recordings for sale; the start of work on motion pictures; and improvements in the recovery of low-grade iron ore. He also pursued a public "War of the Currents" against electrical rival George Westinghouse. Keenly attuned to manufacturing as a way to support the laboratory financially and control his most iconic products, Edison created a new cluster of factories. He kept his manufacturing rights to the phonograph while selling the underlying patents to an outside investor in a deal he would regret. When market pressures led to the consolidation of Edison lighting interests, he sold his factories to the new Edison General Electric Company. These changes disrupted his longtime personal and professional relations even as he planned an iron-mining project that would take him to the New Jersey wilderness for long periods.The ninth volume of the series, Competing Interests explores Edison's inventive and personal pursuits from 1888 to 1889, documenting his responses to technological, organizational, and economic challenges. The book includes 331 documents and hundreds of Edison's drawings, which are all revealing and representative of his life and work in these years. Essays and notes based on meticulous research in a wide range of sources, many only recently available, provide a rich context for the documents.

Biochemical and Molecular Aspects of Selected Cancers, Volume I provides an overview of important topics and prototypes in cancer research. The book consists of papers provided by outstanding investigators in diverse disciplines in different areas of cancer research. This volume focuses on topics relevant to cancers in humans. It covers such topics as tumor-suppressor genes and human neoplasia; protein kinase C in neoplastic cells; and extracellular matrix interactions with tumor-progressing cells: tumor versus cell type-specific mechanisms. Structural and functional characteristics of human melanoma; steroid hormones and hormone receptors in neoplastic diseases; and patterns and significance of genetic changes in neuroblastomas are expounded as well. Oncologists, biochemists, cytologists, and other researchers in allied fields will find the book invaluable.