Abderrezak KHELFI – författare

Les intoxications peuvent �tre individuelles ou collectives, accidentelles ou par m�susage du produit, imm�diates ou � long terme par accumulation des doses ou des effets toxiques, les produits responsables �tant tr�s nombreux.�

Con�u comme un outil d'aide � la d�cision pour une prise en charge rapide et efficace, l'ouvrage aborde les connaissances indispensables en chimie, pharmacologie et toxicologie pour comprendre l'action nocive des toxiques sur les diff�rents organes. L'ouvrage expose �galement les mesures th�rapeutiques � entreprendre face aux intoxications et les mesures pr�ventives � prendre dans les lieux de travail.�

R�dig� par une �quipe pluridisciplinaire, dans une pr�sentation claire et synth�tique, avec de tr�s nombreux tableaux et algorithmes, l'ouvrage constitue une r�f�rence compl�te ainsi qu'une source d'informations pr�cieuse sur les aspects pratiques et analytiques de la toxicologie. Il constitue un outil indispensable pour les toxicologues, les r�animateurs, les urgentistes, mais aussi les m�decins du travail, les pharmaciens et les �tudiants dans ces sp�cialit�s.�

Points cl�s�:

- Les bases fondamentales de la toxicologie�

- Les diff�rents toxiques (drogues, m�dicaments, m�taux, solvants, gaz toxiques, pesticides, plantes toxiques, agents biologiques et autres)�

- Les toxidromes, avec les signes cliniques et les �l�ments diagnostiques et th�rapeutiques

This book pinpoints one of the fastest growing, complex subjects in chemistry and medical science: the dangers of oxidative stress to human beings. It provides a solid background on the chemistry behind the generation of reactive species as well as how reactive species are involved in essential physiological processes and in almost every human disease. It also covers the most recent developments in the study of oxidative and reductive stress (redox stress), including the role of radical and reactive species, novel antioxidant therapies, and methods for assessing free radicals and redox stress. The chapters present concise, yet thorough, summaries of the state-of-the-art methods and techniques that any investigator working in the oxidative/reductive stress field needs to access. The current methodologies including the development of sensors and biosensors for the detection of ROS/RNS/RHS and of biomarkers of redox stress are thoroughly discussed. This book is a useful resource for all researchers and students interested in oxidative stress, molecular biology, and chemistry. Physicians and healthcare professionals interested in understanding the molecular mechanisms underlying the redox stress-related diseases also stand to benefit from this book.

This book pinpoints one of the fastest growing, complex subjects in chemistry and medical science: the dangers of oxidative stress to human beings. It provides a solid background on the chemistry behind the generation of reactive species as well as how reactive species are involved in essential physiological processes and in almost every human disease. It also covers the most recent developments in the study of oxidative and reductive stress (redox stress), including the role of radical and reactive species, novel antioxidant therapies, and methods for assessing free radicals and redox stress. The chapters present concise, yet thorough, summaries of the state-of-the-art methods and techniques that any investigator working in the oxidative/reductive stress field needs to access. The current methodologies including the development of sensors and biosensors for the detection of ROS/RNS/RHS and of biomarkers of redox stress are thoroughly discussed. This book is a useful resource for all researchers and students interested in oxidative stress, molecular biology, and chemistry. Physicians and healthcare professionals interested in understanding the molecular mechanisms underlying the redox stress-related diseases also stand to benefit from this book.