Alberto Salomone – författare

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation.

Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair.

Hair analysis is a reliable and widely used tool to evaluate drug exposure in many fields, including workplace testing, drug abuse history and withdrawal control, post-mortem toxicology, doping control, therapeutic drug monitoring of pharmaceuticals and even environmental exposure to toxic agents. Compounds incorporated into the hair structure resist hair growth and regular washing for several months, leading to a potential chronological trace of exposure, with farther periods corresponding to the hair segments more distant from the hair root. The relentless improvement of analytical procedures and instrumental technologies, together with the continuous introduction of new psychoactive substances, have led to an increasing number of studies and practical applications of hair analysis.

This book is a comprehensive guide to hair analysis from general concepts, ideal for students and those new to the field, to interpretation and advanced methods for experts working in the area. With contributions from world-leading scientists in each field, this book describes state-of-the-art, emerging issues and recent analytical approaches to hair analysis that will serve as an essential tool to clinical and forensic toxicology laboratories across the globe.

Hair analysis is a reliable and widely used tool to evaluate drug exposure in many fields, including workplace testing, drug abuse history and withdrawal control, post-mortem toxicology, doping control, therapeutic drug monitoring of pharmaceuticals and even environmental exposure to toxic agents. Compounds incorporated into the hair structure resist hair growth and regular washing for several months, leading to a potential chronological trace of exposure, with farther periods corresponding to the hair segments more distant from the hair root. The relentless improvement of analytical procedures and instrumental technologies, together with the continuous introduction of new psychoactive substances, have led to an increasing number of studies and practical applications of hair analysis.

This book is a comprehensive guide to hair analysis from general concepts, ideal for students and those new to the field, to interpretation and advanced methods for experts working in the area. With contributions from world-leading scientists in each field, this book describes state-of-the-art, emerging issues and recent analytical approaches to hair analysis that will serve as an essential tool to clinical and forensic toxicology laboratories across the globe.