Alejandro J. Paredes – författare

Hydrogels in Drug Delivery: Advances in the Manufacture, Characterization, and Application of Hydrogels to Address Current Global Healthcare Challenges presents the latest advances in hydrogels, ranging from their basic chemistry to specific application of existing and novel hydrogels in controlled drug delivery and biomedicine. Hydrogels have been increasingly used in the development of novel formulations in a wide variety of therapeutic and monitoring applications. Multidisciplinary work carried out by researchers working in synthetic chemistry, drug delivery, biomedicine and other fields has led to the development of novel polymers, enabling the preparation of hydrogels with adjustable physicochemical properties. Accordingly, these materials offer multiple advantages over other drug delivery systems, including an increased patient compliance by reducing the required number of medication doses, reducing the healing time in injuries, and simplifying patient monitoring by reducing the invasiveness of current methods.Hydrogels in Drug Delivery is an essential resource for graduate students and researchers working within drug delivery and synthetic chemistry, biomedicine, material science, pharmacology, and chemical engineering.

Covers the fundamental mechanisms of drug delivery from a hydrophilic matrixBreaks down interconnections between introductory theory and applied materials chaptersIncludes experimental pictures and links to multimedia features including videos and slides

Hydrogels in Drug Delivery: Advances in the Manufacture, Characterization, and Application of Hydrogels to Address Current Global Healthcare Challenges presents the latest advances in hydrogels, ranging from their basic chemistry to specific application of existing and novel hydrogels in controlled drug delivery and biomedicine. Hydrogels have been increasingly used in the development of novel formulations in a wide variety of therapeutic and monitoring applications. Multidisciplinary work carried out by researchers working in synthetic chemistry, drug delivery, biomedicine and other fields has led to the development of novel polymers, enabling the preparation of hydrogels with adjustable physicochemical properties. Accordingly, these materials offer multiple advantages over other drug delivery systems, including an increased patient compliance by reducing the required number of medication doses, reducing the healing time in injuries, and simplifying patient monitoring by reducing the invasiveness of current methods.Hydrogels in Drug Delivery is an essential resource for graduate students and researchers working within drug delivery and synthetic chemistry, biomedicine, material science, pharmacology, and chemical engineering.- Covers the fundamental mechanisms of drug delivery from a hydrophilic matrix- Breaks down interconnections between introductory theory and applied materials chapters- Includes experimental pictures and links to multimedia features including videos and slides

Nanocrystals have emerged as one of the most versatile and clinically relevant platforms for the delivery of poorly soluble drugs, with several nanocrystal-based products already on the market. Produced through both “bottom-up” and “top-down” approaches, drug nanocrystals possess a large specific surface area that enhances the dissolution and absorption of hydrophobic actives, offering a powerful strategy to improve drug performance. This book presents the fundamental principles of nanocrystal technology alongside their broad applications in modern drug delivery. Chapters explore oral bioavailability enhancement, long-acting injectable therapies, topical and transdermal delivery (including microneedles), ocular and mucosal administration, pulmonary delivery, and strategies for targeting the central nervous system. Each contribution highlights both the opportunities and the challenges of applying nanocrystal formulations across therapeutic areas. Intended for drug delivery scientists in both academia and industry, this volume provides a comprehensive overview of nanocrystal research, development, and translation into innovative therapeutic solutions. By combining rigorous science with insights into clinical and commercial impact, it serves as a valuable resource for researchers, students, and professionals aiming to harness nanocrystals in addressing complex therapeutic needs.