Alejandro Romero Martinez – författare
Visar alla böcker från författaren Alejandro Romero Martinez. Handla med fri frakt och snabb leverans.
3 produkter
3 produkter
E-bok
Engelska, 20242 164 kr
Läs direkt efter köp
Melatonin: A Ubiquitous Pleiotropic Molecule equips researchers with an understanding of the molecular biology of melatonin in plants. The book explores the occurrence of melatonin in several plant species, covering key aspects, including its biosynthesis, physiological function in plant growth and development, and signaling pathways. It then discusses the benefits melatonin has for plant and agricultural development, as well as how it can be utilized as a therapeutic in the treatment of human diseases. The role it can play in the oxidative stress response and circadian rhythm modulation are covered, as well as its nutraceutical potential for human health. The book also covers the importance of melatonin in a range of fields, including drug discovery and disease resistance, agriculture, botany, and biotechnology, and is an ideal reference for researchers across these disciplines.
Examines melatonin’s pivotal role as a signaling molecule, elucidating its involvement in a diverse array of biological responses within plantsCovers essential aspects like melatonin biosynthesis, regulation, antioxidant properties, and its involvement in stress management in plantsProvides an interdisciplinary study of melatonin and its potential uses, including disease management, crop improvement, and nutraceutical developmentAddresses melatonin’s multifaceted role in regulating key physiological processes in the human body, including circadian rhythms, sleep–wake cycles, and neurological protectionDelves into melatonin’s dual role as an immunomodulator influencing immune cells and a powerful antioxidant combating free radicals and alleviating oxidative stressExplores melatonin’s therapeutic and anticancer potential, emphasizing its importance in cardiovascular health, neurology, and cancer research, attributed to its antioxidant and anti-inflammatory characteristics
E-bok
Engelska, 20252 484 kr
Läs direkt efter köp
Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches. - Covers the most significant clinical aspects where melatonin has been shown to be effective- Summarizes research progress and therapeutic applications of melatonin- Provides a platform for researchers from diverse fields to collaborate and advance our understanding of the field
E-bok
PDF, Engelska, 20203 512 kr
Läs direkt efter köp
The exponential influx of scientific research on melatonin is associated with a greater orientation towards the study of the systemic effects of melatonin and their derivatives, as well as their clinical implications. Proof of this fact is summarized in the present compilation, where melatonin is presented as a remarkable agent to counteract most of the physiopathological events that trigger several disorders. The book also collects evidence about melatonin’s interactions with two high-affinity G protein-coupled receptors to provide new pharmacological targets for the treatment of cancer, neurological or endocrine conditions. The present review also includes detailed coverage of molecules with improved safety profiles and melatonin receptor agonists (such as ramelteon, tasimelteon, and agomelatine), and the latest findings on the role of melatonin in protecting plants from abiotic stress, improving their resistance to adverse conditions, regulating several environmental stresses including heat stress, as well as the clinical use of melatonin in the treatment of fertility-related problems and reproductive health. The multiplicity of actions of melatonin, including modulating immune responses and inflammation and maintaining mitochondrial integrity, make this indoleamine a valuable therapeutic agent in the treatment of neurodegeneration, polycystic ovary syndrome, brain ischemia and traumatic brain injury, fibromyalgia, optic neuritis and glaucoma, alone or in combination with other drugs. Melatonin easily crosses the blood-brain and placental barriers. In this sense, this book provides a complete review suggesting that melatonin supplementation should be considered as a potential disease-preventing agent, with the aim of extending pregnancy duration to improve clinical outcomes and prevent fetal brain damage for pregnancy pathologies, such as preeclampsia, intrauterine growth restriction and preterm birth. Within the last few decades, melatonin has emerged in clinical oncology as a naturally occurring bioactive molecule with substantial anticancer properties. In addition, this chronobiotic agent exerts oncostatic effects throughout all stages of tumor growth, from initial cell transformation to mitigation of malignant progression and metastasis. Its therapeutic applications in oral cancer, gastrointestinal pathologies and colorectal cancer are discussed, as well as its applications as an adjuvant for alleviating side-effects and improving the welfare of radio/chemotherapy-treated patients. In the final chapter, the authors summarize the indications for the development of new galenic formulations of melatonin. Thus, different melatonin formulations, such as intranasal solutions, sprays, microspheres, gels and liposomes would allow for the maintenance of endogenous active concentrations for a long time, avoiding poor oral bioavailability.