Alexander L. Green – författare

Autonomic surgery is an important and expanding field within contemporary clinical practice. Surgical therapies influencing the autonomic nervous system have historically entailed disabling various components of its network by injurious methods. More sophisticated techniques have now emerged to allow modulation of neural function by electrical implants or by preservative surgery. This has fuelled the expansion in this field as safer therapies with greater scope for patient benefit have become available. As the potential for precise neural manipulation has advanced, so has the number and diversity of diseases which have become amenable to such therapies. This book reviews the basic science underpinning the autonomic control of various body systems and the state-of-the-art clinical applications by which these systems are surgically modulated in patients today. Clinical chapters include details of the procedure, operative considerations, outcomes, adverse effect profile, post-operative management of such patients and reflections on personal experience. Autonomic surgery can be applied to a wide variety of diseases affecting large numbers of the population such as angina pectoris, hypertension, orthostatic hypotension, sexual dysfunction, regional pain syndromes, headache and epilepsy.

Autonomic surgery is an important and expanding field within contemporary clinical practice. Surgical therapies influencing the autonomic nervous system have historically entailed disabling various components of its network by injurious methods. More sophisticated techniques have now emerged to allow modulation of neural function by electrical implants or by preservative surgery. This has fuelled the expansion in this field as safer therapies with greater scope for patient benefit have become available. As the potential for precise neural manipulation has advanced, so has the number and diversity of diseases which have become amenable to such therapies. This book reviews the basic science underpinning the autonomic control of various body systems and the state-of-the-art clinical applications by which these systems are surgically modulated in patients today. Clinical chapters include details of the procedure, operative considerations, outcomes, adverse effect profile, post-operative management of such patients and reflections on personal experience. Autonomic surgery can be applied to a wide variety of diseases affecting large numbers of the population such as angina pectoris, hypertension, orthostatic hypotension, sexual dysfunction, regional pain syndromes, headache and epilepsy.

Evidence-based medicine is a concept that has come to the fore in the past few years. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new pharmacological therapies are only used when large randomized trials have ''proven'' that a particular drug is better than existing ones. This is also the case in surgical specialties, although surgery has traditionally seen a lack of use of this information, with individual surgeon''s preferences being most influential in treatment choices. However, more recently, there has been a large expansion of trials and studies aimed at providing surgeons with information to guide their choices using firm evidence. This new edition has been revised and expanded to include new data where relevant, and also features a new chapter on pituitary surgery. Landmark Papers in Neurosurgery, Second Edition, remains a key collection of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract key results, and making it essential reading for all neurosurgeons and trainees in the field.

Evidence-based medicine is a concept that has come to the fore in the past few years. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new pharmacological therapies are only used when large randomized trials have ''proven'' that a particular drug is better than existing ones. This is also the case in surgical specialties, although surgery has traditionally seen a lack of use of this information, with individual surgeon''s preferences being most influential in treatment choices. However, more recently, there has been a large expansion of trials and studies aimed at providing surgeons with information to guide their choices using firm evidence. This new edition has been revised and expanded to include new data where relevant, and also features a new chapter on pituitary surgery. Landmark Papers in Neurosurgery, Second Edition, remains a key collection of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract key results, and making it essential reading for all neurosurgeons and trainees in the field.