Alexander Ushenko – författare

Laser Polarization and Autofluorescence Imaging for Biomedical and Clinical Applications addresses the cutting-edge research area of laser and autofluorescence polarimetric visualization combined with sophisticated multi-algorithm digital analysis. The book’s content spans ten detailed sections, covering fundamental theories of Mueller-matrix polarimetry, azimuth-invariant mapping methods, advanced Fourier and wavelet transformations, singular analysis, laser-induced autofluorescence polarimetry, and biomedical system architectures. It culminates with clinical application examples demonstrating early diagnostics of malignancies, type 2 diabetes, albuminuria, cholelithiasis, septic conditions, and forensic determinations such as cause and time of death.This reference offers significant benefits to researchers, biomedical engineers, and medical data analysts by delivering a pioneering synthesis of the latest theoretical concepts and multifunctional digital imaging methods. It equips the audience with objective, highly sensitive digital markers essential for accurate, rapid preclinical diagnostics, thereby advancing precision medicine and evidence-based clinical practice in biomedical optics.Develops new analytical principles for comprehensive biophysical polarization and autofluorescence imagingDescribes architecture and operational principles of advanced laser polarimetric diagnostic systemsPresents multi-algorithmic digital analysis, including statistical, correlation, fractal, singular, Fourier, and wavelet methodsProvides objective digital markers for high-precision preclinical diagnostics of multiple diseasesDemonstrates clinical applications in cancer, diabetes, albuminuria, septic conditions, and forensic investigations

This book explores the early-stage detection of cancer using polarized light. It discusses the diverse properties of the light (temporal and spatial coherence, polarization, fluorescence, etc.) that can be used non-invasively as an optical technique for recognizing precancerous lesions, which could become a reliable and accurate method for cancer screening. The search for the effective means for cancer screening is of particular interest to scientific and medical communities, because cancer takes its toll around the globe with no respect for age or gender. Early detection of the disease is a key factor in increasing the survival rate and patients’ quality of life.