Alfredo Cesario – författare

The book provides a multidisciplinary outlook on using Artificial Intelligence (AI)-based solutions in the field of Personalized Medicine and its transitioning towards Personalized Digital Medicine.

The first section integrates different perspectives on AI-based solutions and highlights their potential in biomedical research and patient care. In the second section, the authors present several real-world examples that demonstrate the successful use of AI technologies in various contexts. These include examples from digital therapeutics, in silico clinical trials, and network pharmacology. In the final section of the book, the authors explore future directions in AI-enhanced biomedical technologies and discuss emerging technologies such as blockchain, quantum computing and the “metaverse”. The book includes discussions on the ethical, regulatory, and social implications for an AI-based personalized medicine.

The integration of heterogeneous disciplines brings together multiple stakeholders and decision makers involved in the personalization of care. Clinicians, students, and researchers from academia and the industry can benefit from this book, since it provides foundational knowledge to drive advances in personalized biomedical research and health care.

This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods.  Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.