Ali Cinar - Böcker

Illustrating techniques in model development, signal processing, data reconciliation, process monitoring, quality assurance, intelligent real-time process supervision, and fault detection and diagnosis, Batch Fermentation offers valuable simulation and control strategies for batch fermentation applications in the food, pharmaceutical, and chemical industries. The book provides approaches for determining optimal reference trajectories and operating conditions; estimating final product quality; modifying, adjusting, and enhancing batch process operations; and designing integrated real-time intelligent knowledge-based systems for process monitoring and fault diagnosis.

The latest advances in process monitoring, data analysis, and control systems are increasingly useful for maintaining the safety, flexibility, and environmental compliance of industrial manufacturing operations.Focusing on continuous, multivariate processes, Chemical Process Performance Evaluation introduces statistical methods and modeling techniques for process monitoring, performance evaluation, and fault diagnosis.This book introduces practical multivariate statistical methods and empirical modeling development techniques, such as principal components regression, partial least squares regression, input-output modeling, state-space modeling, and modeling process signals for trend analysis. Then the authors examine fault diagnosis techniques based on episodes, hidden Markov models, contribution plots, discriminant analysis, and support vector machines. They address controller process evaluation and sensor failure detection, including methods for differentiating between sensor failures and process upset. The book concludes with an extensive discussion on the use of data analysis techniques for the special case of web and sheet processes. Case studies illustrate the implementation of methods presented throughout the book.Emphasizing the balance between practice and theory, Chemical Process Performance Evaluation is an excellent tool for comparing alternative techniques for process monitoring, signal modeling, and process diagnosis. The unique integration of process and controller monitoring and fault diagnosis facilitates the practical implementation of unified and automated monitoring and diagnosis technologies.

This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep.Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.