Alireza Minagar - Böcker

With recent advances of modern medicine, more people reach the "elderly age� around the globe, and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into the pathogenesis of this devastating group of diseases.

Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS.

The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS.

It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.

Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MS Discusses the roles of neurodegeneration and neuroregeneration in MS and related diseases Authored and edited by international leaders in the field of MS research

Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics.

Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

Comprehensively reviews the latest developments in neuroinflammation and neuro-inflammatory diseases Written for researchers and clinical practitioners in clinical neuroscience, neurology and immunology Includes new chapters on Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury

This issue of the Neurologic Clinics is dedicated to the cerebellum and includes articles on its functional neuroanatomy and different cerebellar pathologies. Among the various reviews contained in this issue, there are two particularly unique articles devoted to the role of the cerebellum in human cognition and psychiatric diseases. Other topics include: the Cerebellum and Sleep; Toxic-Metabolic, Nutritional, and Medicinal-Induced Disorders of Cerebellum; Multiple Sclerosis and the Cerebellum; and Infections of the Cerebellum, among others.

This important subject of Diagnosis of and Treatment for Neurobehavioral manifestations of neurologic disease is directed by three leaders of this field - Dr. Alizeza Minagar, Dr. Glen Finney, and Dr. Kenneth Heilman. Topics include: Neurobehavioral testing for mental status; Behavioral neurology of vascular neurology; Alzheimer's disease; Frontotemporal dementia; Traumatic brain injury; Parkinsonian Syndromes (e.g., Parkinson's disease, Lewy body dementia, progressive supranuclear palsy, corticobasal disease, multisystem atrophy); Behavioral neurology of multiple sclerosis and autoimmune encephalopathies; Infectious Diseases (Neuro-AIDS, Neurosyphilis, HSV); Neurobehavioral aspects of systemic disease; Neurobehavioral aspects of epilepsy; Behavioral neurology aspects of nutritional deficiencies; Neurobehavioral aspects of mitochondrial disease; and Medicinal-induced behavioral disorders.

This issue of Neurologic Clinics features 17 articles that address the neurologic implications of systemic illnesses. Articles include neurologic presentations of infective endocardititis; neurologic presentations of acid-base imbalance, electrolyte abnormalities, and endocrine emergencies; neurologic presentation of renal disease; neurologic manifestations of systemic lupus erythematosus in children and adults; neurologic complications of respiratory disease; neurologic presentations of nutritional deficiencies; neurologic presentations of gastrointestinal disease; neurotoxicity of radiation therapy; neurologic presentation of lyme disease and syphilis; neurologic aspects of drug abuse; neurologic manifestations of transplant complications; neurologic presentations of sarcoidosis; neurologic presentations of fungal infections; neurologic presentations of cardiac disease; neurologic presentation of AIDS; neurologic presentation of systemic vasculitis; and neurologic presentations of hepatic disease.

Many neurologic disorders can appear in quick and severe forms that require immediate medical attention. This issue of Neurologic Clinics features 14 articles on conditions that commonly present acutely, such as epilepsy, headache, visual loss, nervous system infections, ischemic stroke, head and spinal cord injury, and intracranial hemorrhage.

As a core part of the central nervous system, the spinal cord has a distinctive role in the etiology and exacerbation of common and less common neurologic disorders. This issue of Neurologic Clinics will look at the spinal cord's involvement in disorders arising generally in the CNS, as well as disorders based within the cord itself. Articles include: Spinal cord: A review of functional neuroanatomy; Infections of spinal cord; Multiple sclerosis and spinal cord; Transverse myelitis; Neuromyelitis optica; Vascular disorders of spinal cord; Spine and spinal cord trauma; Imaging of spinal cord: General principles; Toxic, nutritional, and metabolic deficiencies of spinal cord; Spinal cord: Motor neuron diseases; Spinal cord tumors: New views and future directions; Spinal cord and spasticity: A mechanistic view; Cervical spondylosis and stenosis; Autonomic nervous system disorders and spinal cord; Stiff person syndrome: What is new?; Sleep disorders in patients with spinal cord injury.

The Year Book of Neurology and Neurosurgery brings you abstracts of the articles that reported the year's breakthrough developments in neurology and neurosurgery, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Readers will find information on a range of topics, including Movement Disorders, Infectious Diseases of the Nervous System, Neoplastic Disease, Pediatric Neurology and Neurosurgery, Cerebrovascular, Neuro-oncology, and Spine. The Year Book of Neurology and Neurosurgery is published annually in June.

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.

This thoroughly updated edition covers all clinical aspects of neuroinflammation.  The latest developments in pathogenesis  and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade.  Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.