Andrew P. Robinson – författare

With climate change and increasing globalisation of trade and travel, the risks presented by invasive pests and pathogens to natural environments, agriculture and economies have never been greater, and are only increasing with time. Governments world-wide are responding to these increased threats by strengthening quarantine and biosecurity. This book presents a comprehensive review of risk-based techniques that help policy makers and regulators protect national interests from invasive pests and pathogens before, at, and inside national borders. Selected from the research corpus of the Centre of Excellence for Biosecurity Risk Analysis at the University of Melbourne, this book provides solutions that reflect scientific rigour coupled with practical, hands-on applications. Focusing on surveillance, stochastic modelling, intelligence gathering, decision making and risk communication, the contents combine the strengths of risk analysts, mathematicians, economists, biologists and statisticians. The book presents tested scientific solutions to the greatest challenges faced by quarantine and biosecurity policy makers and regulators today.

With climate change and increasing globalisation of trade and travel, the risks presented by invasive pests and pathogens to natural environments, agriculture and economies have never been greater, and are only increasing with time. Governments world-wide are responding to these increased threats by strengthening quarantine and biosecurity. This book presents a comprehensive review of risk-based techniques that help policy makers and regulators protect national interests from invasive pests and pathogens before, at, and inside national borders. Selected from the research corpus of the Centre of Excellence for Biosecurity Risk Analysis at the University of Melbourne, this book provides solutions that reflect scientific rigour coupled with practical, hands-on applications. Focusing on surveillance, stochastic modelling, intelligence gathering, decision making and risk communication, the contents combine the strengths of risk analysts, mathematicians, economists, biologists and statisticians. The book presents tested scientific solutions to the greatest challenges faced by quarantine and biosecurity policy makers and regulators today.

Biosecurity: A Systems Perspective provides an overview of biosecurity as a system of related components, actors, and risks. This book—directed to the biosecurity practitioner, generalist scientist, and student—introduces overall features of the biosecurity system while walking the reader through the most up-to-date research on each step of the continuum (i.e. pre-border, border, and post-border activities). This book, which explicitly incorporates economic and social dimensions as well as varied decision-making contexts, paves the way for a more systemic approach to biosecurity risk management. The work spans statistics, ecology, mathematics, economics, veterinary science, human medicine, and sociology, involving collaborators across government, academia, and the private sector.This book uses a broad definition of biosecurity, rather than solely focusing on plant health, animal health, security, or one step of the biosecurity system (e.g. surveillance). As such, this book is a one-stop shop for readers interested in all aspects of biosecurity.The content and language are accessible to a wide range of audiences, including generalist scientists, biosecurity practitioners, and graduate students. More complex content is introduced in standalone boxes or chapters.The book follows a clear, simple structure within and among chapters (i.e. following the structure of the biosecurity system), making it a preferred option for graduate students.This book introduces novel cross-cutting themes, such as the importance of economic efficiency and institutional and social factors, going beyond the traditional science-based approach to biosecurity.Written in partnership with government agency practitioners, this book uses on-the-ground case studies to demonstrate how biosecurity principles are applied in practice.The book addresses challenges common to regulators in general, namely efficient regulation in uncertain and rapidly changing environments with multiple stakeholders who have—at times—conflicting priorities.Chapters 6, 7, 8, 9 and 14 of this book are freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Biosecurity: A Systems Perspective provides an overview of biosecurity as a system of related components, actors, and risks. This book—directed to the biosecurity practitioner, generalist scientist, and student—introduces overall features of the biosecurity system while walking the reader through the most up-to-date research on each step of the continuum (i.e. pre-border, border, and post-border activities). This book, which explicitly incorporates economic and social dimensions as well as varied decision-making contexts, paves the way for a more systemic approach to biosecurity risk management. The work spans statistics, ecology, mathematics, economics, veterinary science, human medicine, and sociology, involving collaborators across government, academia, and the private sector.This book uses a broad definition of biosecurity, rather than solely focusing on plant health, animal health, security, or one step of the biosecurity system (e.g. surveillance). As such, this book is a one-stop shop for readers interested in all aspects of biosecurity.The content and language are accessible to a wide range of audiences, including generalist scientists, biosecurity practitioners, and graduate students. More complex content is introduced in standalone boxes or chapters.The book follows a clear, simple structure within and among chapters (i.e. following the structure of the biosecurity system), making it a preferred option for graduate students.This book introduces novel cross-cutting themes, such as the importance of economic efficiency and institutional and social factors, going beyond the traditional science-based approach to biosecurity.Written in partnership with government agency practitioners, this book uses on-the-ground case studies to demonstrate how biosecurity principles are applied in practice.The book addresses challenges common to regulators in general, namely efficient regulation in uncertain and rapidly changing environments with multiple stakeholders who have—at times—conflicting priorities.Chapters 6, 7, 8, 9 and 14 of this book are freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Biosecurity: A Systems Perspective provides an overview of biosecurity as a system of related components, actors, and risks. This book—directed to the biosecurity practitioner, generalist scientist, and student—introduces overall features of the biosecurity system while walking the reader through the most up-to-date research on each step of the continuum (i.e. pre-border, border, and post-border activities). This book, which explicitly incorporates economic and social dimensions as well as varied decision-making contexts, paves the way for a more systemic approach to biosecurity risk management. The work spans statistics, ecology, mathematics, economics, veterinary science, human medicine, and sociology, involving collaborators across government, academia, and the private sector.

This book uses a broad definition of biosecurity, rather than solely focusing on plant health, animal health, security, or one step of the biosecurity system (e.g. surveillance). As such, this book is a one-stop shop for readers interested in all aspects of biosecurity. The content and language are accessible to a wide range of audiences, including generalist scientists, biosecurity practitioners, and graduate students. More complex content is introduced in standalone boxes or chapters. The book follows a clear, simple structure within and among chapters (i.e. following the structure of the biosecurity system), making it a preferred option for graduate students. This book introduces novel cross-cutting themes, such as the importance of economic efficiency and institutional and social factors, going beyond the traditional science-based approach to biosecurity. Written in partnership with government agency practitioners, this book uses on-the-ground case studies to demonstrate how biosecurity principles are applied in practice. The book addresses challenges common to regulators in general, namely efficient regulation in uncertain and rapidly changing environments with multiple stakeholders who have—at times—conflicting priorities.

Chapters 6, 7, 8, 9 and 14 of this book are freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Biosecurity: A Systems Perspective provides an overview of biosecurity as a system of related components, actors, and risks. This book—directed to the biosecurity practitioner, generalist scientist, and student—introduces overall features of the biosecurity system while walking the reader through the most up-to-date research on each step of the continuum (i.e. pre-border, border, and post-border activities). This book, which explicitly incorporates economic and social dimensions as well as varied decision-making contexts, paves the way for a more systemic approach to biosecurity risk management. The work spans statistics, ecology, mathematics, economics, veterinary science, human medicine, and sociology, involving collaborators across government, academia, and the private sector.

This book uses a broad definition of biosecurity, rather than solely focusing on plant health, animal health, security, or one step of the biosecurity system (e.g. surveillance). As such, this book is a one-stop shop for readers interested in all aspects of biosecurity. The content and language are accessible to a wide range of audiences, including generalist scientists, biosecurity practitioners, and graduate students. More complex content is introduced in standalone boxes or chapters. The book follows a clear, simple structure within and among chapters (i.e. following the structure of the biosecurity system), making it a preferred option for graduate students. This book introduces novel cross-cutting themes, such as the importance of economic efficiency and institutional and social factors, going beyond the traditional science-based approach to biosecurity. Written in partnership with government agency practitioners, this book uses on-the-ground case studies to demonstrate how biosecurity principles are applied in practice. The book addresses challenges common to regulators in general, namely efficient regulation in uncertain and rapidly changing environments with multiple stakeholders who have—at times—conflicting priorities.

Chapters 6, 7, 8, 9 and 14 of this book are freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

With climate change and increasing globalisation of trade and travel, the risks presented by invasive pests and pathogens to natural environments, agriculture and economies have never been greater, and are only increasing with time. Governments world-wide are responding to these increased threats by strengthening quarantine and biosecurity. This book presents a comprehensive review of risk-based techniques that help policy makers and regulators protect national interests from invasive pests and pathogens before, at, and inside national borders. Selected from the research corpus of the Centre of Excellence for Biosecurity Risk Analysis at the University of Melbourne, this book provides solutions that reflect scientific rigour coupled with practical, hands-on applications. Focusing on surveillance, stochastic modelling, intelligence gathering, decision making and risk communication, the contents combine the strengths of risk analysts, mathematicians, economists, biologists and statisticians. The book presents tested scientific solutions to the greatest challenges faced by quarantine and biosecurity policy makers and regulators today.

With climate change and increasing globalisation of trade and travel, the risks presented by invasive pests and pathogens to natural environments, agriculture and economies have never been greater, and are only increasing with time. Governments world-wide are responding to these increased threats by strengthening quarantine and biosecurity. This book presents a comprehensive review of risk-based techniques that help policy makers and regulators protect national interests from invasive pests and pathogens before, at, and inside national borders. Selected from the research corpus of the Centre of Excellence for Biosecurity Risk Analysis at the University of Melbourne, this book provides solutions that reflect scientific rigour coupled with practical, hands-on applications. Focusing on surveillance, stochastic modelling, intelligence gathering, decision making and risk communication, the contents combine the strengths of risk analysts, mathematicians, economists, biologists and statisticians. The book presents tested scientific solutions to the greatest challenges faced by quarantine and biosecurity policy makers and regulators today.

Forest Analytics with R combines practical, down-to-earth forestry data analysis and solutions to real forest management challenges with state-of-the-art statistical and data-handling functionality. Theauthors adopt a problem-driven approach, in which statistical and mathematical tools are introduced in the context of the forestry problem that they can help to resolve. All the tools are introduced in the context of real forestry datasets, which provide compelling examples of practical applications.The modeling challenges covered within the book include imputation and interpolation for spatial data, fitting probability density functions to tree measurement data using maximum likelihood, fitting allometric functions using both linear and non-linear least-squares regression, and fitting growth models using both linear and non-linear mixed-effects modeling. The coverage also includes deploying andusing forest growth models written in compiled languages, analysis of natural resources and forestry inventory data, and forest estate planning and optimization using linear programming. The book would be ideal for a one-semester class in forest biometrics or applied statistics for natural resources management. The text assumes no programming background, some introductory statistics,and very basic applied mathematics.

Forest Analytics with R combines practical, down-to-earth forestry data analysis and solutions to real forest management challenges with state-of-the-art statistical and data-handling functionality. Theauthors adopt a problem-driven approach, in which statistical and mathematical tools are introduced in the context of the forestry problem that they can help to resolve. All the tools are introduced in the context of real forestry datasets, which provide compelling examples of practical applications.The modeling challenges covered within the book include imputation and interpolation for spatial data, fitting probability density functions to tree measurement data using maximum likelihood, fitting allometric functions using both linear and non-linear least-squares regression, and fitting growth models using both linear and non-linear mixed-effects modeling. The coverage also includes deploying andusing forest growth models written in compiled languages, analysis of natural resources and forestry inventory data, and forest estate planning and optimization using linear programming. The book would be ideal for a one-semester class in forest biometrics or applied statistics for natural resources management. The text assumes no programming background, some introductory statistics,and very basic applied mathematics.

Vaccine research and development is advancing at an unprecedented pace, with an increasing emphasis on rational design based upon a fundamental und- standing of the underlying molecular mechanisms. The aim of this volume is to provide a selection of contemporary protocols that will be useful to both novice and advanced practitioner alike. The variety of procedures required to design, develop, produce, and assess a vaccine is immense and covers aspects of ch- istry, biochemistry, molecular biology, cell biology, and immunology. No single volume can hope to cover these topics exclusively. Rather, here we attempt to provide a methods sourcebook focusing on hands-on practical advice. Comp- mentary and background information may be found in other volumes in the Me- ods in Molecular Medicine series. Of particular interest are volumes on Dendritic Cell Protocols, Interleukin Protocols, Vaccine Adjuvants, and DNA Vaccines. Since the publication of the first edition of Vaccine Protocols there have been major advances, particularly in the areas of bacterial genomics, antig- specific T-cell quantification, genetic manipulation of vaccine vectors, the h- nessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. Hence, the extensive revision of this edition with new chapters on live viral vaccine vectors, atte- ated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes, and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-t- art methods in vaccinology.

Vaccine research and development is advancing at an unprecedented pace, with an increasing emphasis on rational design based upon a fundamental und- standing of the underlying molecular mechanisms. The aim of this volume is to provide a selection of contemporary protocols that will be useful to both novice and advanced practitioner alike. The variety of procedures required to design, develop, produce, and assess a vaccine is immense and covers aspects of ch- istry, biochemistry, molecular biology, cell biology, and immunology. No single volume can hope to cover these topics exclusively. Rather, here we attempt to provide a methods sourcebook focusing on hands-on practical advice. Comp- mentary and background information may be found in other volumes in the Me- ods in Molecular Medicine series. Of particular interest are volumes on Dendritic Cell Protocols, Interleukin Protocols, Vaccine Adjuvants, and DNA Vaccines. Since the publication of the first edition of Vaccine Protocols there have been major advances, particularly in the areas of bacterial genomics, antig- specific T-cell quantification, genetic manipulation of vaccine vectors, the h- nessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. Hence, the extensive revision of this edition with new chapters on live viral vaccine vectors, atte- ated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes, and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-t- art methods in vaccinology.

The production of a book devoted to Vaccine Protocols has proved to be a complex task; the variety of procedures required to design, develop, pro­ duce, and assess a vaccine is immense and covers aspects of chemistry, bio­ chemistry, molecular biology, and immunology. Many of the previous volumes in the Methods in Molecular Biology series provide the background required for work on vaccines; of particular interest are the volumes on Immunochemi­ cal Protocols, Practical Molecular Virology, Proteins, and Nucleic Acids. In the volume on Vaccine Protocols, we have tried to cover the latest scientific methods for the design, production, and assessment of vaccines against viruses, bacteria, and parasites. Essentially, the volume is comprised of three basic chapter types. First, a number of chapters describe in detail the development and production of vac­ cines by specific techniques, including genetic manipulation of viruses or bac­ teria to produce live attenuated vaccines or inactivated toxins, and the production of synthetic peptides and conjugate vaccines. Second, a similar number of chapters describe more general techniques that can be used for the formulation, delivery, and assessment of immune responses to vaccines.