Anil K. Suresh – författare

This brief gives a concise overview of nanoparticles and their microbial toxicity. It introduces various nanoparticles that are considered lethal to microbial cells (bacteria, virus and fungus) placing an emphasis on metal and metal oxide nanoparticles. The synthesis procedures (physical, chemical, microbial) that are often employed in their fabrication are also outlined. The interaction of various nanoparticles with microbes is described with attention given to the role of additives in the form of solvents, surfactants, capping materials. Commonly used experimental and analytical techniques that are often used to evaluate and determine the toxicity of nanoparticles towards different microorganisms are presented and comparative assessments on the differences between these procedures are described. The brief ends by explaining the toxicity of metal and metal oxide nanoparticles to microorganisms.

This brief gives a concise overview of nanoparticles and their microbial toxicity. It introduces various nanoparticles that are considered lethal to microbial cells (bacteria, virus and fungus) placing an emphasis on metal and metal oxide nanoparticles. The synthesis procedures (physical, chemical, microbial) that are often employed in their fabrication are also outlined. The interaction of various nanoparticles with microbes is described with attention given to the role of additives in the form of solvents, surfactants, capping materials. Commonly used experimental and analytical techniques that are often used to evaluate and determine the toxicity of nanoparticles towards different microorganisms are presented and comparative assessments on the differences between these procedures are described. The brief ends by explaining the toxicity of metal and metal oxide nanoparticles to microorganisms.

Although interactions between nanoparticles and microorganisms in the environment are unavoidable and commonplace, it is still not clear what potential effects they may have. Metallic Nanocrystallites and their Interface with Microbial Systems not only illustrates how microbes and these particular nanoparticles interact but also it describes the consequences of these interactions. This brief discusses the impact of gold, silver, zinc oxide, and cerium oxide nanoparticles on the growth and viability of both Gram-negative and Gram-positive bacterium. Moreover, it analyses the relationship between bacterial growth inhibition, reactive oxygen species generation, the regulation of transcriptional stress genomes, and the toxicity of these materials. Finally, it reviews the specific metallic nanomaterials and highlights their modes of synthesis, reactivity at surfaces, and the importance of assay procedures in determining their toxicity levels. Various microscopy techniques used to determine their mechanisms of action are also presented. Metallic Nanocrystallites and their Interface with Microbial Systems will be a valuable source to the scientific and industrial community as well as to students and researchers in microbiology, biotechnology, nanotechnology, toxicology, materials science, biomedical engineering, cell and molecular biology.

Although interactions between nanoparticles and microorganisms in the environment are unavoidable and commonplace, it is still not clear what potential effects they may have. Metallic Nanocrystallites and their Interface with Microbial Systems not only illustrates how microbes and these particular nanoparticles interact but also it describes the consequences of these interactions. This brief discusses the impact of gold, silver, zinc oxide, and cerium oxide nanoparticles on the growth and viability of both Gram-negative and Gram-positive bacterium. Moreover, it analyses the relationship between bacterial growth inhibition, reactive oxygen species generation, the regulation of transcriptional stress genomes, and the toxicity of these materials. Finally, it reviews the specific metallic nanomaterials and highlights their modes of synthesis, reactivity at surfaces, and the importance of assay procedures in determining their toxicity levels. Various microscopy techniques used to determine their mechanisms of action are also presented. Metallic Nanocrystallites and their Interface with Microbial Systems will be a valuable source to the scientific and industrial community as well as to students and researchers in microbiology, biotechnology, nanotechnology, toxicology, materials science, biomedical engineering, cell and molecular biology.

This book presents the latest technology of sustainable nanomaterials for applications as drug delivery cargos in tackling various inflammatory diseases. The chapters in this book describe nanotechnology-based drug delivery strategies, the mechanistic insights of nanoformulations and their application in managing inflammation diseases such as rheumatoid arthritis, ulcerative colitis, cancer and neurological disorder. It looks into the challenges of using nanomaterials-based smart materials for enhanced therapeutic efficacy while maintaining safe and sustainable procedures. The book is divided into three main sections: A) Fundamental of smart nanocarriers and nanoformulations targeted drug delivery in inflammatory disease; B) Smart nano drug delivery therapy- an emerging approach towards inflammatory diseases and C) Novel nano delivery strategies in targeting major inflammatory diseases. The book targets early researchers and clinical practitioners who are interested in the management and treatment of inflammatory diseases using nanotechnology-based drug delivery systems.