Ankit Kumar Singh - Böcker

Enhanced approaches for using plant-derived molecules as a more promising cancer treatment alternative, with lower costs and fewer side effects Plant-derived Anticancer Drugs discusses the current scenario of cancer, the limitations of synthetic drugs, and the potential of plant-derived molecules in cancer treatment, highlighting a variety of approaches, such as biodegradable nano and quantum dot-based materials, that enhance the therapeutic efficacy of plant-derived molecules to improve solubility, applicability, target-specific delivery, and overall efficacy. The book begins by discussing the preclinical and clinical utilization of synthetic drugs in cancer therapy, highlighting their mechanisms of action, therapeutic outcomes, limitations, and future perspectives. The book then provides a snapshot of the major drugs approved by the FDA which have historically served as the cornerstone of center treatment, and provides a clinical evidence-based analysis of their survival outcomes. Next, the current role, acceptance, advancements, and challenges of using plant-derived molecules in cancer therapy are reviewed. Contributed to by international experts in the field, Plant-derived Anticancer Drugs continues to cover sample topics including: Advancements in anti-cancer drug development due to genomics, biotechnology, and systems biologyIntegrative approaches which leverage the cytotoxic precision of synthetic drugs alongside the multitargeted and often less toxic nature of phytochemicalsOptimization of phytochemicals with high anticancer potential to reduce drug discovery timelines and associated costsIntegration of Artificial Intelligence (AI) and plant-derived bioactive compoundsAbility of plant-derived molecules and herbal formulations to target multiple pathways involved in cancer progression, such as cell proliferation, apoptosis, angiogenesis, and metastasisPlant-derived Anticancer Drugs is a completely comprehensive and up-to-date reference on the subject, ideal for natural products chemists, medicinal chemists, biochemists, and cancer researchers in academia and industry. The book is also valuable reading for graduates and undergraduates studying nanotechnology, phytochemistry, pharmacology, oncology, and toxicology.

The fragments of the plastics smaller than 5 mm are called microplastics. These are widely distributed contaminants in aquatic, terrestrial, and aerial environments. Microplastics are released into the environment due to the extensive use of plastics and microplastics for various purposes, such as mulching, commercial organic fertiliser, and cosmetics. In addition, microplastics are also released from industries like polymer, textiles, and transport industries. The mismanagement of plastic garbage also builds up in the environment and releases microplastics.Microplastics not only act as contaminants but also act as vectors for numerous harmful chemical and biological pollutants, such as heavy metals, persistent organic pollutants, and pathogens, which have been linked to detrimental effects on the health of aquatic and terrestrial ecosystems.The present book will discuss the research carried out by the great scientific community working in the field of microplastic pollution in the soil, air, and water, as well as their potential remediation strategies. The readers would be able to find a loop between the significant sources of microplastic pollution, their impact on the biosphere, and solutions in one place.