Antoinette Maassen van den Brink - Böcker

This book focuses on the influence of sex and gender in migraine, presenting new insights in basic science as well as their clinical relevance.  As migraine is roughly three times more common in women than in men, and also highly depends on hormonal milestones – such as menarche, menstruation, pregnancy and menopause – particular attention is devoted to the role of female sex hormones in this disease.  The first chapters present general data on gender-related differences in migraine such as epidemiology, comorbidities and related risks. Furthermore, while several chapters focus on the role of female sex hormones in migraine-triggering mechanisms at a basic scientific level (e.g. cranial circulation), ample attention is also paid to the clinical relevance of such mechanisms and to the best clinical treatment for migraine patients.As the first book entirely devoted to this topic, it will be of interest to researchers and practitioners in the fields of neurology, internalmedicine, endocrinology, physiology and pharmacology.

Intended to promote a more appropriate and modern therapeutic approach to migraine management, this book is the first to deal with monoclonal antibodies in this context. Authored by the most respected migraine experts from around the globe and drawing on the lessons learned in both clinical trials and clinical practice, it reviews the current state of knowledge on this important therapeutic innovation, which has produced impressive data in randomized controlled trials, and the efficacy and safety of which have been confirmed in day-to-day real-world use. Given its scope, the book will appeal to a broad range of specialists, including pharmacologists, clinical pharmacologists, neurologists and internists, but also to residents and medical students.