Ashish Dwivedi – författare

Unable to consult a library for information, the healthcare practitioner must learn to effectively manage knowledge while thinking on their toes.Knowledge Management (KM) holds the key to this dilemma in the healthcare environment.

This book comprehensively reviews essential oils and fragrances and their role in cosmetics and personal care products. The initial chapters define essential oils, outline their types, and discuss their widespread use in cosmetics, delving into the specific fragrance compounds that contribute to personal care products' sensory and functional attributes. The book addresses critical safety and toxicological assessments, including risk assessment methodologies, toxicological testing requirements, and allergen labeling and management. It emphasizes Good Manufacturing Practices (GMP), providing guidelines and certification processes for product quality and safety. The book provides an overview of key international regulatory bodies and standards, such as ISO and IFRA, and discusses efforts towards harmonization and establishing international standards. It presents strategies for global compliance, including case studies of multinational companies that have successfully navigated regulatory challenges. Furthermore, the book examines innovations and regulatory responses, particularly the impact of new technologies like synthetic biology. This book is aimed at professionals in the cosmetic industry, such as product developers, regulatory specialists, and marketing professionals.Key featuresExplores the essential oils and fragrances in detail, covering definitions, types, and their roles in cosmetics and personal care productsGuides safety assessments, Good Manufacturing Practices (GMP), labeling, and advertising regulationsReviews key international regulatory bodies like ISO and IFRA and discusses efforts towards standard harmonizationIncludes case studies of multinational companies and offers strategies for global complianceExamines the impact of new technologies like synthetic biology and current trends towards sustainability and transparency

Unable to consult a library for information, the healthcare practitioner must learn to effectively manage knowledge while thinking on their toes.Knowledge Management (KM) holds the key to this dilemma in the healthcare environment.

This book highlights the problem of UV-R-induced photocarcinogenesis and its molecular mechanism. It covers different photosensitive xenobiotics (drugs, cosmetics, and environmental pollutants) and their photosensitization mechanisms under ambient UV-R exposure. It also summarizes the role of nanotechnology in skin cancer remedies. It provides a brief overview of the various novel nanocarriers for cosmeceuticals like nanoemulsions, liposomes, solid lipid nanoparticles (SLNs), dendrimers, inorganic nanoparticles, nanocrystals, etc., nanotechnology-based cosmeceutical products which are available in the market. It highlights the possible health hazards caused by nanoparticles on exposure of nano-based cosmetics and describes the recent regulatory rules applied to avoid the nanotoxicity.

This book provides detailed and comprehensive mechanistic insights of the various risk factors that lead to the ischemic stroke and the novel therapeutic interventions against it. The first section discusses the different ischemic cerebral stroke-induced inflammatory pathways and dysfunctionality of blood-brain barrier. The later sections of the book deals with the role of endoplasmic reticulum stress and mitophagy in cerebral stroke and introduces the different neuroimaging techniques such as Computed tomography (CT), Magnetic resonance imaging (MRI), Positron emission tomography (PET) and Single-Photon emission computed tomography (SPECT) that are used to identify the arterial blockages. The final section comprises of chapters that focus on various neuroprotective strategies and emerging therapeutic interventions for combating stroke pathophysiology. The chapters cover the role of stem cell therapy, the therapeutic effect of low-frequency electromagnetic radiations (LF-EMR), and implications of non-coding RNAs such as micro-RNAs as the biomarkers for diagnosis, prognosis, and therapy in ischemic stroke.

This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer.

This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer.  It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.

This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer.  It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.

This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer.

This book provides recent advances in the understanding of the central processes in the resolution of inflammation.

This book provides recent advances in the understanding of the central processes in the resolution of inflammation. It also describes the active, specialized pathways that bring the resolution of inflammation. Further, the book examines the key molecular and cellular events that are involved in the resolution of inflammation processes involved in tissue repair and regain of physiological function. Importantly, it sheds light on the cellular and molecular processes through which conventional inflammatory cytokines control mammalian tissue repair and regeneration. It also explores the perturbation of processes that are involved in the resolution of inflammation with aging and reviews clinical trials of anti-inflammatory and immunomodulatory therapies.  Towards the end, the book discusses the role of inflammation in the development and progression of cancer. This book is an invaluable resource for scientists, academicians, and research scholars interested in the latest cutting-edge knowledge in the field of immunology, inflammation, inflammation resolution, and inflammatory diseases.​

The book delves into various aspects of the hair care industry, providing a comprehensive understanding of hair throughout history, its anatomy and physiology, genetics and molecular mechanisms of hair color, and the raw materials used in the industry.

The book delves into various aspects of the hair care industry, providing a comprehensive understanding of hair throughout history, its anatomy and physiology, genetics and molecular mechanisms of hair color, and the raw materials used in the industry. It explores the diverse range of hair care products, including oils, dyes, lotions, and serums, and emphasizes the importance of global regulatory approaches to ensure consumer health and safety, particularly in relation to nano-formulations and synthetic hair care products. The book also addresses the safety and efficacy of herbal care products from a global regulatory perspective. Furthermore, it examines the impact of the microbiome on hair care products, highlighting the opportunities and challenges in complying with global regulations. The evaluation of hair care product safety is discussed within a global context, exploring different models and methods. The book also focuses on the journey of hair care products from laboratory testing to market, emphasizing clinical and preclinical assessments in compliance with global regulations. It highlights the role of ex-vivo hair follicle models in ensuring the safety and effectiveness of hair care products while providing a global regulatory framework. Additionally, the book explores the potential of artificial intelligence in predicting hair product toxicity, taking a global perspective. It delves into omics approaches for hair toxicity assessment, discussing current advances and future directions in this field. The next generation of hair products is also explored, with a focus on innovations that prioritize safe and healthy consumer choices. Finally, the book provides an overview of global regulatory frameworks for the hair care industry, including key agencies and guidelines. It serves as a valuable resource for professionals and researchers in the field, offering insights into the historical, scientific, and regulatory aspects of hair care products and their impact on consumer health and safety.

Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.

Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing.