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This book explains important ideas behind medical uses of statistics without burdening the reader with the technical details of mathematical manipulations. It is based on conversations with John Bailar and Frederick Mosteller of the Department of Biostatistics of the Harvard School of Public Health.
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This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.