Benno Runnebaum – författare

Durch den Einsatz von Gonadotropin-Releasinghormon (GnRH)- -Analoga in der Behandlung von Endometriose und Uterus myomatosus haben sich f}r die medikament|se Therapie neue M|glichkeiten er|ffnet; im Vergleich zu den bekannten Be- -handlungsformen mit Gestagenen oder Androgenen bedeutet dies eine grunds{tzliche Weiterentwicklung in der Therapie. Neben den allgemeinen Wirkungsprinzipien von GnRH-Analoga werden im vorliegenden Buch aktuelle Ergebnisse aus der klinischen Forschung mit diesen neuen therapeutischen Konzepten zusammenfassend dargestellt.

Reproductive health - the new concept involving an integrated approach to all inter­ ventions dealing with the reproductive process and organs - has been the subject of two recent world forums: the 1994 International Conference on Population and Development in Cairo and the 1995 Women's Conference in Beijing. It is therefore very timely for Benno Runnebaum and Thomas Rabe to produce the English translation of the second edition of their text book Gynecological Endo­ crinology and Reproductive Medicine. The two volumes bring the reader up to date on the enormous progress mad- in just a few years - in the field of reproduction. A selected group of coauthors have provided the breadth of knowledge necessary to cover fields as diverse as physiology, endocrinology, endoscopic surgery, ultrasonography, genetics, and on­ cology. The first volume describes physiological events, especially the complex interplay of factors leading to ovulation occurring during menstrual cycle, and the patholog­ ical changes that can alter it. This is preceded by a careful review of the wide range of hormones active in the female reproductive process, their mechanisms of action, interactions with receptors, therapeutic applications, indications, contrain­ dications, and modes of action. Sex differentiation, puberty, fertility, and reproduc­ tion are carefully detailed, including management of the hyperandrogenic state and other disorders, including endocrine oncology. Special care is taken in describing the control of human fertility, its many facets, methods, and problems.

Contraceptives have always provided ground for controversy. This book describes and discusses latest findings concerning the advantages as well as hazard and risk factors of contraception. The clinical impact of oral contraceptives on metabolism is particularly highlighted. In addition, behavioral methods, intrauterine devices, implants and modern approaches in animal and clinical research in the field of immunization against pregnancy are considered. Last, but not least, the book summarizes the complex ethical, religious and political aspects of family planning and contraception.

Contraceptives have always provided ground for controversy. This book describes and discusses latest findings concerning the advantages as well as hazard and risk factors of contraception. The clinical impact of oral contraceptives on metabolism is particularly highlighted. In addition, behavioral methods, intrauterine devices, implants and modern approaches in animal and clinical research in the field of immunization against pregnancy are considered. Last, but not least, the book summarizes the complex ethical, religious and political aspects of family planning and contraception.

Dedication to Professor Dr. med. Dr. h. c. mult. Benno Runnebaum on his 65th Anniversary The name of Benno Runnebaum is closely tied to the status of gynaecological endocrinology and reproductive medicine. Therefore, we would like to dedicate this conference book entitled "Fertility Control" to him in recognition of his achieve- ments. Who is Benno Runnebaum? Benno Runnebaum was born on 22 July, 1933, in Ruschendorf, Germany. After taking his A-levels, he studied medicine in Munster, Bonn and Cologne. He graduated from Cologne University in 1961 and then prepared his doctoral thesis on the "Identificati- on and quantification of progesterone, 20a-dihydroprogesterone, 20~-dihydroproge- sterone and 17a-hydroxyprogesterone in the plasma of human placental blood". This Benno Runnebaum VI Preface publication was the first to describe the progestin cycle in the feto-placental unit. His thesis was supported by Professor Dr. med. Dr. h. c. Josef Zander. It was graded "sum- ma cum laude" and won him a scholarship from the National Institute of Health for training in steroid biochemistry at the Biochemical Institute in Salt Lake City (Profes- sor Samuels) in 1962 and 1963.After his return to Germany he worked at the Univer- sity Women's Hospital of Cologne. He received his further specialist training in 1964 at the Heidelberg Women's Hospital, under the chairmanship of his teacher, Professor Zander.

Our knowledge of reproductive medicine has expanded rapidly since the birth of Louise Brown, the first baby to be conceived by in vitro fertilization, which was performed by Professors Steptoe and Ed­ wards in Bourn Hall, England, in 1978. Hardly a year goes by without the development of a new or the modification of an existing method of assisted reproduction. Within a relatively short period, in vitro fertilization has been introduced into the treatment of female infertility. Intracytoplasmic sperm injection has also created new opportunities for the treatment of male infertility. This manual takes stock of the techniques of assisted reproduc­ tion that are available today. Competent authors from various centers present, in a concise way, their tried-and-tested procedures, so that the latter can be readily implemented. Due to different legal regulations, the scope of assisted re­ production is much more limited in Germany than in many other countries. For example, whereas only three embryos may be con­ ceived and transferred in Germany, such restrictions do not exist in several other European countries and the United States. Further­ more, heterologous fertilization, oocyte donation, and surrogate motherhood are banned in Germany. We are glad to have been able to recruit many international ex­ perts to present the various fields of assisted reproduction from their perspective. We hope this book will help to establish the different therapies and achieve a wide distribution.

Die Nachfolgebände der "Gynäkologischen Endokrinologie" (1987) signalisieren bereits im Titel die Erweiterung des Fachgebiets, die aus den zahlreichen Neuentwicklungen der letzten Jahre resultiert. Hierzu zählen z.B. der Nachweis und die Bedeutung neuer Hormone, neue Funktionsteste, die Therapie mit weiblichen Sexualhormonen, die Untersuchung von Umwelteinwirkungen sowie diagnostische und operative Techniken der Fertilitätschirurgie. Damit ist für den deutschsprachigen Raum der aktuelle Kenntnisstand dieses Spezialgebiets umfassend und ausführlich dargestellt. Mit zahlreichen Graphiken und Tabellen sowie ausgezeichnetem Bildmaterial sind deshalb die Bände Gynäkologische Endokrinologie und Fortpflanzungsmedizin für den Gynäkologen in der Klinik wie in der Praxis ein wichtiger Begleiter.

Die Nachfolgebände der "Gynäkologischen Endokrinologie" (1987) signalisieren bereits im Titel die Erweiterung des Fachgebiets, die aus den zahlreichen Neuentwicklungen der letzten Jahre resultiert. Hierzu zählen z.B. der Nachweis und die Bedeutung neuer Hormone, neue Funktionsteste, die Therapie mit weiblichen Sexualhormonen, die Untersuchung von Umwelteinwirkungen sowie diagnostische und operative Techniken der Fertilitätschirurgie. Damit ist für den deutschsprachigen Raum der aktuelle Kenntnisstand dieses Spezialgebiets umfassend und ausführlich dargestellt. Mit zahlreichen Graphiken und Tabellen sowie ausgezeichnetem Bildmaterial sind deshalb die Bände Gynäkologische Endokrinologie und Fortpflanzungsmedizin für den Gynäkologen in der Klinik wie in der Praxis ein wichtiger Begleiter.

Diese beiden Nachfolgebände der "Gynäkologischen Endokrinologie" (1987) signalisieren bereits im Titel die Erweiterung des Fachgebiets, die aus den zahlreichen Neuentwicklungen der letzten Jahre resultiert. Hierzu zählen z.B. der Nachweis und die Bedeutung neuer Hormone, Wachstumsfaktoren, neue Funktionsteste, die Therapie mit weiblichen Sexualhormonen, die Untersuchung von Umwelteinwirkungen sowie diagnostische und operative Techniken der Fertilitätschirurgie.Mit diesen beiden Büchern sind Sie umfassend über den aktuellen Kenntnisstand dieser Spezialgebiete informiert. Mit ihren zahlreichen Graphiken und Tabellen sowie ihrem ausgezeichneten Bildmaterial werden die Bände Gynäkologische Endokrinologie und Fortpflanzungsmedizin für Ärzte in der Klinik wie auch in der Praxis ein ständiger Begleiter sein.