Bernard Pullman – författare

Molecular Associations in Biology provides information pertinent to molecular biology. This book discusses several topics, including DNA replication, calculation of intermolecular energies, and thermodynamic parameters of polynucleotides. Organized into 35 chapters, this book starts with an overview of the specific association of the purine and pyrimidine bases in the nucleic acids, which provides the basis for storage, expression, and transmission of genetic information. This text then explores the secondary structures, interactions, and replication processes of nucleic acids. Other chapters consider the complex biological process of protein synthesis. This book discusses as well the methods of photodynamic action, which is significant in detecting energy transfer from dye to the biomolecule and identifying the free radicals produced. The final chapter deals with the macroscopic properties of molecular systems, which refer to such concepts as volume, mass, pressure, temperature, and pH. This book is a valuable resource for biophysicists, organic chemists, biochemists, and biologists.

Frontiers in Physicochemical Biology documents the proceedings of an international symposium held in celebration of the 50th anniversary of the Institut de Biologie Physico-Chimique, (Fondation Edmond de Rothschild) in Paris, May 23-27, 1977. The symposium was organized to cover the main topics of modern day molecular biology and biophysics, which are also the major disciplines researched at the Institute. The contributions made by researchers at the symposium are organized into four parts. Part I contains papers on the physical chemistry of fundamental biomolecules. Part II presents studies on physicochemical aspects of the mechanisms of genetic expression. Part III examines the biochemistry of oxygen and hemoglobin. Part IV deals with the study of organized systems.

The main theme of the symposium reported in this book was the presentation and discussion of the direct and indirect evidence available on the three-dimensional structure of membrane proteins and on the interactions relevant to their functioning. Among the topics discussed are the lessons of the known 3D structures, the prospects in 3D structure determination (by X-rays, electron microscopy, neutron scattering, NMR, optical methods, site-directed mutagenesis, theoretical calculations and modeling, etc) and the interactions with lipids. The originality of the Symposium, reflected in the content of the book, was to bring together well-known specialists in the biochemistry of the proteins considered (bacteriorhodopsin, receptors, acetylcholine esterase, glycophorine, porines, etc) and experts in the physicochemical, chemical and theoretical methods utilized.

Gathering together a number of experts in the world, the 27th Jerusalem Symposium was devoted to the theme of the modelling of biomolecular structures and mechanisms. As a result of recent growth in both importance and audience, the papers contained in this volume present an evaluation of the status of the present knowledge in this field. The main topics covered by this year's Symposium include nucleic acids and their interactions, proteins and their interaction, membranes and their interactions, enzymatic processes and the pharmacological and medical aspects of these subjects. Readers should benefit from the interdisciplinary approach which provides coverage of both theoretical and experimental advances.