Brett J. Bordini – författare

Dr. Kliegman and Dr. Bordini have written a primer on Undiagnosed and Rare Diseases in Children. Leading experts have presented the current knowledge in the following areas: How Doctor's Think: Common Diagnostic Errors in Clinical Judgment; Team-Based Approach to Undiagnosed and Rare Diseases; Ending a Diagnostic Odyssey: Family Education Counselling and Their Response to Eventual Diagnosis; Eczema and Urticaria as Manifestations of Undiagnosed and Rare Diseases; Usual and Unusual Manifestations of Familial Hemophagocytic and Langerhans Cell Histiocytosis Syndromes; When Autistic Behavior Suggests a Disease Other than Classic Autism; Non-classic Inflammatory Bowel Disease in Young Infants; IPEX and Other Disorders; Usual and Unusual Presentation of Mitochondrial Disorders; When to Suspect Auto-inflammatory/Recurrent Fever Syndromes; Primary and Secondary Causes of Autonomic Dysfunction; Usual and Unusual Manifestations of Systemic and CNS Vasculitis; Fever of Unknown Origin; Differentiating Familial Neuropathies from Guillain-Barre Syndrome; and Munchausen by Proxy: A Factitious Undiagnosed Disease. Readers will come away with cutting-edge information to use immediately in their clinical management of patients.

In collaboration with Consulting Editor, Dr. Lucky Jain, Drs. Robert Kliegman and Bret Bordini �have put together topics that provide a current clinical update on the treatment and management of undiagnosed and rare diseases in the neonate. �Expert authors have contributed clinical review articles on the following topics: �Neonatal Liver Failure; Neonatal Autoinflammatory Disorders; Rare or Unusual Dermatologic Disorders In Neonates; Neonatal Immune Deficiency; Congenital Diarrhea Syndromes; Nonimmune Hydrops; DNA Depletion Syndromes; Genomic Approach to Dysmorphology Syndromes; Nonimmune Anemias; Severe Metabolic Crisis (Metabolic Acidosis, Unresponsive Hypoglycemia, Hyperammonemia); Heterotaxia Syndromes; Neonatal Appendicitis; Avoiding Diagnostic Errors in Neonatology; and Differentiating Congenital Myopathy from Congenital Muscular Dystrophy. �Readers will come away with the information they need to improve outcomes in the neonate.

Patients don't present with a disease; they present with symptoms.� Using a practical, symptom-based organization,�Nelson Pediatric Symptom-Based Diagnosis: Common Diseases and their Mimics, 2nd Edition,�offers�authoritative guidance on differential diagnosis and treatment�of diseases and disorders in children and adolescents, and covers�the symptoms you're likely to see�in practice,�their mimics, and�uncommon disorders. Drs. Robert M. Kliegman, Heather Toth, Brett J.�Bordini, and Donald Basel walk you through�what to consider and how to proceed�when faced with common symptoms such as cough, fever, headache, autistic-like behaviors, chronic pain, chest pain, gait disturbances, and much more.

In this issue of�Critical Care Clinics,�guest�editors�Drs.�Robert M.�Kliegman�and Brett J.�Bordini�bring�their�considerable expertise to the topic of�Undiagnosed and Rare Diseases in Critical Care. Top experts in the field cover key topics such�as critical genetic arrhythmia disorders,�uncommon causes of rhabdomyolysis,��status epilepsy syndromes,�autoimmune encephalitis, rapid-onset paralysis and weakness,�and more.