C. John Harris – författare
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2 produkter
2 produkter
Attrition in the Pharmaceutical Industry
Reasons, Implications, and Pathways Forward
Inbunden, Engelska, 2015
1 598 kr
Skickas inom 5-8 vardagar
With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency. Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attritionTackles a problem that adds billions of dollars to drug development programs and health care costsGuides discovery and development scientists through R&D stages, teaching requirements and reasons why drugs can failDiscusses potential ways forward utilizing new approaches and opportunities to reduce attrition
2 654 kr
Skickas inom 5-8 vardagar
Multi-target drug discovery (MTDD) is an emerging area of increasing interest to the drug discovery community. Drugs that modulate several targets have the potential for an improved balance of efficacy and safety compared to single targets agents. Although there are a number of marketed drugs that are thought to derive their therapeutic benefit by virtue of interacting with multiple targets, the majority of these were discovered accidentally. Written by world renowned experts, this is the first book to gather together knowledge and experiences of the rational discovery of multi-target drugs. It describes the current state of the art, the achievements and the challenges of the field and importantly the lessons learned by researchers to date and their application to future MTDD.