Chris Wild - Böcker

"I think this is an excellent book–I recommend it to anyone involved in molecular epidemiology... The 26 chapters are written by topic specialists, in an explanatory, east to read style." –BTS Newsletter, Summer 2009 "This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiological studies.  One of the strengths in this book is the extensive array of practical illustrative examples, and it would also in my opinion have useful potential as a teaching text." –American Journal of Human Biology, March 2009 With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research.  Covers categories of biomarkers of exposure, susceptibility and diseaseIncludes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studiesEmphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologiesDemonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracyDiscusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposureExplores practical elements of conducting population studies, including biological repositories and ethicsMolecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles.

'The authentic inside track... Gripping' Lemn Sissay'An important and hugely powerful book... So inspiring, I loved The State of It' Neil Morrissey'Incredibly compelling' Denise WelchCAN WE FIX HOW WE LOOK AFTER CHILDREN IN CARE?Government cuts, unregulated care homes, inadequate staff training - campaigner and care home consultant Chris Wild has seen it all. The low standards and frequent abuse of children in care has long been a focal point of his loud message: we are failing our young people and something needs to change.Chris delves deep into the lives of care home kids, from experiences with county lines, drugs, trafficking, knife crime, gang violence to child exploitation and sexual abuse. He tells the stories of the voiceless, the children who have been left behind, compounded by his own experiences of growing up in care.How is the care system failing our young people and controlling just who and what they can become? What help do we really give children after their time in care is over, left to fend for themselves? Is it too late to fix the state of it?URGENT AND CRITICAL, THE STATE OF IT WILL BE THE MOST IMPORTANT BOOK YOU READ THIS YEAR.In support of Become, the charity for children in care and young care leavers, a charity registered in England and Wales, charity number 1010518.