Cy A. Stein – författare
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3 produkter
3 produkter
Häftad, Engelska, 1998
3 697 kr
Skickas inom 5-8 vardagar
Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.
Häftad, Engelska, 2006
1 381 kr
Skickas inom 5-8 vardagar
The potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are explored in this volume, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. The focus is on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides. Specific chapters address designing better siRNAs, splice switching oligonucleotides, selective delivery of oligonucleotides, and medicinal drugs by receptor-mediated endocytosis, development of a function overriding siRNA silencing in mammalian cells, transcription factor decoys, and modified oligonucleotide hybridization and genetic insertion. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Del 34 - Annals of the New York Academy of Sciences
Oligonucleotide Therapeutics
4th Annual Meeting, Volume 1175
Häftad, Engelska, 2009
1 138 kr
Tillfälligt slut
Oligonucleotides modulate gene-specific expression within cells and can be used to identify genes involved in diseases. Continuing developments in oligonucleotide research have begun to unleash their potential as therapeutic agents. Contributions from basic researchers in molecular biology, cell biology, nucleic acid chemistry, pharmacology, and applied therapeutics present new technologies in the field of oligonucleotide research and are organized into sections focusing on small RNA-mediated gene silencing, miRNA, oligonucleotide chemistry and new technologies, delivery strategies, immunorecognition of nucleic acids, drug and therapeutic development, aptamers and other evolved systems, and preclinical models and clinical programs.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.