Dankmar Bohning - Böcker

Providing reliable information on an intervention effect, meta-analysis is a powerful statistical tool for analyzing and combining results from individual studies. Meta-Analysis of Binary Data Using Profile Likelihood focuses on the analysis and modeling of a meta-analysis with individually pooled data (MAIPD). It presents a unifying approach to modeling a treatment effect in a meta-analysis of clinical trials with binary outcomes.After illustrating the meta-analytic situation of an MAIPD with several examples, the authors introduce the profile likelihood model and extend it to cope with unobserved heterogeneity. They describe elements of log-linear modeling, ways for finding the profile maximum likelihood estimator, and alternative approaches to the profile likelihood method. The authors also discuss how to model covariate information and unobserved heterogeneity simultaneously and use the profile likelihood method to estimate odds ratios. The final chapters look at quantifying heterogeneity in an MAIPD and show how meta-analysis can be applied to the surveillance of scrapie. Containing new developments not available in the current literature, along with easy-to-follow inferences and algorithms, this book enables clinicians to efficiently analyze MAIPDs.

Capture-recapture methods have been used in biology and ecology for more than 100 years. However, it is only recently that these methods have become popular in the social and medical sciences to estimate the size of elusive populations such as illegal immigrants, illicit drug users, or people with a drinking problem. Capture-Recapture Methods for the Social and Medical Sciences brings together important developments which allow the application of these methods. It has contributions from more than 40 researchers, and is divided into eight parts, including topics such as ratio regression models, capture-recapture meta-analysis, extensions of single and multiple source models, latent variable models and Bayesian approaches. The book is suitable for everyone who is interested in applying capture-recapture methods in the social and medical sciences. Furthermore, it is also of interest to those working with capture-recapture methods in biology and ecology, as there are some important developments covered in the book that also apply to these classical application areas.

Capture-recapture methods have been used in biology and ecology for more than 100 years. However, it is only recently that these methods have become popular in the social and medical sciences to estimate the size of elusive populations such as illegal immigrants, illicit drug users, or people with a drinking problem. Capture-Recapture Methods for the Social and Medical Sciences brings together important developments which allow the application of these methods. It has contributions from more than 40 researchers, and is divided into eight parts, including topics such as ratio regression models, capture-recapture meta-analysis, extensions of single and multiple source models, latent variable models and Bayesian approaches. The book is suitable for everyone who is interested in applying capture-recapture methods in the social and medical sciences. Furthermore, it is also of interest to those working with capture-recapture methods in biology and ecology, as there are some important developments covered in the book that also apply to these classical application areas.