David Abraham – författare

Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based.

This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

FLIGHT FROM ALBEROBELLO is a story about John and Rose who fall in love in Italy at the turn of the 20th century. Rose is sent to America to forget about John, who, becomes an outcast. Beaten and driven from the tenant farm that he worked with his father, John, sets a course of action that will help him find Rose. Fearing for his life, John leaves Alberobello and follows Rose to America where he risks the ultimate sacrifice.

The novel focuses on Johns struggle as he attempts to meld old traditions into a new world laced with conflicting attitudes and values. After years of personal discord, John discovers that he, subconsciously, harbors many of the same intolerances that once forced him from the land of his birth.

FLIGHT FROM ALBEROBELLO chronicles, fictitiously, the life of an immigrant in a small upstate New York City. It is a story secreted in the roots of many who were brave enough to seek a new life, in an unknown land, fraught with uncertainty and contradiction. For immigrants flooding to American at the start of the 20th century, it was a new frontier.

Arterial disease and inflammation are fundamental causes of many medical conditions. Recently, there have been several major advances in our understanding of the causes of diseases affecting the heart, lungs, kidneys, skin and blood vessels. The role of endothelium derived growth factors, nitric oxide and other messengers in vascular disease has been more clearly defined. New treatments targeting these molecular disorders are being used with beneficial effects. Further progress depends on a combined approach embracing basic and clinical research so that treatments of common, important diseases can be designed intelligently and logically. "Vascular Complications in Human Disease" presents our understanding of vascular disease, in reviews of the main strands of basic and clinical research written by leading international experts. It also identifies routes for further fruitful research and development. This concise and carefully edited book, avoiding repetition, includes the full spectrum of basic research which is not covered in other textbooks.