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17 produkter
17 produkter
224 kr
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3 590 kr
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Examining the implications and practical implementation of multi-disciplinary International Conference on Harmonization (ICH) topics, this book gives an integrated view of how the guidelines inform drug development strategic planning and decision-making.• Addresses a consistent need for interpretation, training, and implementation examples of ICH guidelines via case studies• Offers a primary reference point for practitioners addressing the dual challenge of interpretation and practical implementation of ICH guidelines• Uses case studies to help readers understand and apply ICH guidelines• Provides valuable insights into guidelines development, with chapters by authors involved in generating or with experience implementing the guidelines• Includes coverage of stability testing, analytical method validation, impurities, biotechnology drugs and products, and good manufacturing practice (GMP)
178 kr
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Cirencester is one of the most remarkable towns in Britain. From its Roman beginnings around AD 75, when it was classed second only in importance to London, to its current status as the ‘Capital of the Cotswolds’, it has always punched well above its weight. The ‘A-side’ of its history as a small market town which developed at the centre of the Cotswold wool trade is well documented, but what about its ‘ ip-side’? Much of the town’s fascinating history has either been overlooked or lies hidden below the surface. Well-known local author David Elder delves deep into Cirencester’s lost, forgotten and hidden histories, recounting some remarkable stories. Learn, for example, about some of Cirencester’s minor celebrities and local characters, including the Victorian female astronomer who became a national expert in sunspots and solar eclipses. He also unearths fascinating facts, celebrating, for example, the town’s accolade of having the UK’s oldest public outdoor swimming pool in continuous use, and explaining why it was important for passengers travelling on the railways around the mid-nineteenth century to understand that Cirencester time was 7 ½ minutes earlier than London time.With tales of remarkable characters, unusual events and tucked-away or disappeared historical buildings and locations, Secret Cirencester will appeal to all those with an interest in the history of this town in Gloucestershire.
178 kr
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From its Saxon beginnings to the severe floods of 2007, Tewkesbury is one of Britain’s most remarkable towns. It is well known for its Norman abbey of cathedral-like proportions and the great battle which proved to be one of the most decisive in the Wars of the Roses, but its history contains much more that has often been overlooked. In this book local author David Elder delves deep into Tewkesbury’s lost, forgotten and hidden histories, recounting some remarkable stories. Learn, for example, about some of the town’s minor celebrities and local characters – from the seaman who carried Admiral Nelson’s wounded body to the cockpit of HMS Victory, to the miserly tanner who amassed a great fortune ‘for no higher purpose than the sordid desire of seeing it uselessly accumulate’. The author unearths fascinating facts, celebrating the town’s tradition of nonconformity which led to more than one riot, and provides fascinating insights into how the town’s inhabitants were once comically portrayed as having sharp features because it was assumed that they lived on the town’s famous hot, pungent mustard!With tales of remarkable characters, unusual events and tucked-away or disappeared historical buildings and locations, Secret Tewkesbury will appeal to all those with an interest in the history of this town in Gloucestershire.
178 kr
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Stroud has been an important market town in the Cotswolds for centuries. At the heart of the five valleys, its prosperity was founded on the wool trade in the Middle Ages. During the Industrial Revolution, the town became a textile centre with numerous mills built along its streams. The canal network facilitated trade and industry in the town, as did the arrival of Brunel’s Great Western Railway. The town is renowned today for its historic buildings and steep streets and has become an independent cultural centre with a strong environmental community, which even boasted its own currency for a while in recent years. Through the centuries Stroud’s unusual history has encompassed the country’s oldest anti-slavery memorial, Huguenot and Jewish communities, a Victorian Communist colony, the last pistol duel in England, food riots, suffragettes, suffragists and much more.With tales of remarkable characters, unusual events and tucked-away or disappeared historical buildings and locations, Secret Stroud will appeal to all those with an interest in the history of this Gloucestershire town.
178 kr
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With its own traditions and strong sense of identity and independence, the Forest of Dean appears as a separate, almost secret, part of Gloucestershire. Some of its ancient history has only recently come to light, after lying hidden beneath the forest canopy for millennia, but its more recent past also evokes surprise and wonder. Local author David Elder takes the reader on an A–Z tour around the region’s history, uncovering the stories of its buildings, famous (and infamous) sons and daughters, natural features and fascinating old routes and thoroughfares. From its highest point, once known as Yarleton Hill, to the shores of its two vast rivers, we discover hidden places, many mentioned in the Domesday Book, characterful rocks and ancient trees. Alongside freeminers, rebel leaders, trade union rights campaigners, community doctors, composers, poets and pioneering metallurgists we find enterprising members of a family who gave their name to the household brand of a famous malted drink, and a wealthy merchant and, later, Lord Mayor of London immortalised in folklore.A–Z of the Forest of Dean reveals the history behind the area, its towns and villages, industries and the people connected with it. Alongside the famous historical connections, are unusual characters, tucked-away places and unique events that are less well-known. Fully illustrated throughout, this book will appeal to all those with an interest in this spectacular corner of England.
173 kr
Kommande
The Cotswolds area has played an important role in history through the ages and women from the Cotswolds have been at the forefront of many significant moments in the area’s history and associated with many of its special places. In this book the stories of these remarkable women are explored; some of them are well known and others deserve greater attention. Amongst them are the Gloucestershire nurse and poet of the First World War Eva Dobell and textile designer Dorothy Larcher; social worker and women’s rights campaigner Lilian Faithfull and suffragist Harriet Mcllquham; the astronomer Elizabeth Brown and educational pioneer Dorothea Beale as well as many other names and stories.Extraordinary Cotswolds Women is a celebration of some of the remarkable women in the history of the Cotswolds. Their stories include tales of tales of writers and artists, reformers and scientists, builder, farmers and royalty and much more. All those who would like to know more about the history of the Cotswolds will find this book of interest.
181 kr
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A 'stuccoed town in the Regency manner', a watering place that became the most fashionable resort in England following George III's visit, or a place of Bath-chairs where ex-colonial officers came to die? A vibrant town of festivals and fashionable shops, a Mecca for horse racing, international music, cricket and world-renowned colleges, or a quiet retreat for luxurious gardens and cultural events? Cheltenham has never suffered an identity crisis. It has simply re-invented itself through the ages. How better to portray Cheltenham's unique, evolving personality than through pictures that tell 'thousands of words' juxtaposed with les mots justes culled from some of our most acclaimed writers. From Jane Austen to Ann Yearsley, writers both modern and old, as diverse as George Orwell, Laurie Lee, George Bernard Shaw, C. Day-Lewis, Cobbett, Defoe, Scott, Trollope, Thackeray, Dickens, Byron and Betjeman, have heaped praise on the town or damned it, been spellbound by its beauty or sneered at its laziness and opulence. Famous explorers and composers have written about it as their birthplace, while others have written about it as a place to visit, whether as poets, essayists or even relatives of German philosophers. Love or hate it, they have always remember their experience of Cheltenham.
178 kr
Skickas inom 11-20 vardagar
The best way to explore a town is on foot accompanied by an expert guide. In this comprehensive set of illustrated walks catering for all abilities Cheltenham's history and literature are woven together to create a rich tapestry of fascinating insights that will surprise locals and inspire visitors. Cheltenham goes back a long way, well before George III's visit secured it as a most fashionable place for the beau monde to visit. However, it has also constantly reinvented itself as a place of learning, of sport, of tourism and leisure, not to mention its attraction as a place for business and work. Indeed Cheltenham could almost claim 'city status', such is its importance and influence in certain fields. Walking around this town is the best way to appreciate where the town has come from and how it has moved with the times. Where else could you find Assembly Rooms (now a bank) which once held concerts by Paganini and Liszt, and readings by Dickens and Thackeray?
173 kr
Skickas inom 11-20 vardagar
From a small market town to its heyday as a fashionable watering place and recognition as ‘the most complete Regency town in Britain’, through to its subsequent reinvention as a centre for religion, education, shopping and festivals, Cheltenham has a proud and distinctive identity. This extraordinary history is embodied in the buildings that have shaped the town, from the medieval church (now its Minster) and the Montpellier Rotunda, where a young Gustav Holst performed, to the world’s first (outside of London) purpose-built Masonic hall and one of the country’s most iconic buildings of the modern era, the GCHQ Doughnut.In this unique study well-known local author David Elder guides the reader on a tour of its greatest treasures, revealing that Cheltenham’s history is sometimes complex but never dull.
178 kr
Skickas inom 11-20 vardagar
The ‘A-side’ of Cheltenham’s history as a fashionable Regency spa and subsequent reinvention as a town of colleges, churches and festivals is well documented, but what about its ‘flip-side’? Much of the town’s fascinating history has either been overlooked or lies hidden below the surface. Well-known local author David Elder delves into Cheltenham’s lost, forgotten and hidden histories, unearthing fascinating facts and recounting some remarkable stories. Learn, for example, about some of Cheltenham’s minor celebrities and local characters – from the man who sold his wife for little more than 18 pence to the concert pianist who claimed to be the reincarnation of Franz Liszt, while not forgetting the person who led to the ‘discovery’ of Jeeves not long before perishing at the Battle of the Somme. Secret Cheltenham reveals the lesser-known aspects of this remarkable town.
Historic England: Gloucester
Unique Images from the Archives of Historic England
Häftad, Engelska, 2018
168 kr
Skickas inom 11-20 vardagar
This illustrated history portrays one of England’s finest cities. It provides a nostalgic look at Gloucester’s past and highlights the special character of some of its most important historic sites.The photographs are taken from the Historic England Archive, a unique collection of over 12 million photographs, drawings, plans and documents covering England’s archaeology, architecture, social and local history. Pictures date from the earliest days of photography to the present and cover subjects from Bronze Age burials and medieval churches to cinemas and seaside resorts.Gloucester’s history stretches back to the Romans and the foundation of St Peter’s Abbey by the Anglo-Saxons. In the Middle Ages Gloucester played an important role in the country, becoming a wealthy borough and a centre of royal power. As a port on the River Severn it benefited from the wool trade as well as other industries, and this wealth continued in later centuries. Today the city is a fascinating mixture of old and new, with its imposing cathedral – one of the homes of the Three Choirs Festival – redeveloped Docklands area, and numerous historical buildings from various centuries found alongside striking modern structures. This book will help you to discover its remarkable history.
Historic England: Cheltenham
Unique Images from the Archives of Historic England
Häftad, Engelska, 2018
168 kr
Skickas inom 11-20 vardagar
This illustrated history portrays one of England’s finest towns. It provides a nostalgic look at Cheltenham’s past and highlights the special character of some of its most important historic sites. The photographs are taken from the Historic England Archive, a unique collection of over 12 million photographs, drawings, plans and documents covering England’s archaeology, architecture, social and local history. Pictures date from the earliest days of photography to the present and cover subjects from Bronze Age burials and medieval churches to cinemas and seaside resorts.Historic England: Cheltenham shows the town as it once was, from its grand streets and squares to its famous tree-lined promenades and gardens surrounding its spas. Once the ‘most complete Regency town in Britain’, Cheltenham became the most fashionable resort in England following George III’s visit and has enjoyed centuries of prosperity based on the discovery of its natural mineral springs. But the town has not rested on its laurels and is now a vibrant centre of festivals and fashionable shops, a Mecca for horse racing, international music, cricket and world-renowned schools and colleges. Cheltenham is one of the country’s most visited towns and this book will help you discover its colourful and fascinating history.
Historic England: Gloucestershire
Unique Images from the Archives of Historic England
Häftad, Engelska, 2019
168 kr
Skickas inom 11-20 vardagar
This illustrated history portrays one of England’s finest counties. It provides a nostalgic look at Gloucestershire’s past and highlights the special character of some of its most important historic sites.The photographs are taken from the Historic England Archive, a unique collection of over 12 million photographs, drawings, plans and documents covering England’s archaeology, architecture, social and local history. Pictures date from the earliest days of photography to the present and cover subjects from Bronze Age burials and medieval churches to cinemas and seaside resorts.The county of Gloucestershire is one of the most varied in the country. Divided by the valley of the River Severn, the ancient Forest of Dean in the west of the county was home to coal mining for many years. To the east, the Cotswold Hills grew wealthy in the Middle Ages through the wool trade and many towns and villages have a rich heritage of historic buildings, from Chipping Camden and the mill town of Stroud to Cirencester, which was founded by the Romans. The two largest settlements are the cathedral city of Gloucester and Georgian Cheltenham, but other historical towns are to be found throughout the county, from Tewkesbury to Berkeley, Thornbury and Chipping Sodbury.
271 kr
Skickas inom 5-8 vardagar
303 kr
Skickas inom 5-8 vardagar
Atlas of Dermatopathology
Synopsis and Atlas of Lever’s Histopathology of the Skin
Inbunden, Engelska, 2020
2 573 kr
Skickas inom 7-10 vardagar
Offering a highly visual, systematic approach to diagnosing skin diseases, Atlas of Dermatopathology: Synopsis and Atlas of Lever’s Histopathology of the Skin, 4th Edition, is an ideal reference tool or teaching aid for dermatopathologists, pathologists, dermatologists, and trainees. This unique atlas uses a pattern-based approach to differential diagnosis, clearly organized according to what is seen on a microscopic slide. More than 1600 high-quality images assist in the understanding of cutaneous reaction patterns and diagnosis. Classifies patterns according to location, reaction patterns, and cell type if applicable, including diseases that have been recently described.Color-codes each chapter for consistency, helping you navigate quickly to the information you need.Compares “look-alike” diseases in easy-to-reference tables.Includes multiple color photomicrographs for each disease, in addition to providing an online image bank.Enrich Your Ebook Reading ExperienceRead directly on your preferred device(s),such as computer, tablet, or smartphone.Easily convert to audiobook,powering your content with natural language text-to-speech.