David Robertson – författare

Does it seem you've formulated a rock-solid strategy, yet your firm still can't get ahead? If so, construct a solid foundation for business execution--an IT infrastructure and digitized business processes to automate your company's core capabilities. In Enterprise Architecture as Strategy: Creating a Foundation for Business Execution, authors Jeanne W. Ross, Peter Weill, and David C. Robertson show you how. The key? Make tough decisions about which processes you must execute well, then implement the IT systems needed to digitize those processes. Citing numerous companies worldwide, the authors show how constructing the right enterprise architecture enhances profitability and time to market, improves strategy execution, and even lowers IT costs. Though clear, engaging explanation, they demonstrate how to define your operating model--your vision of how your firm will survive and grow--and implement it through your enterprise architecture. Their counterintuitive but vital message: when it comes to executing your strategy, your enterprise architecture may matter far more than your strategy itself.

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health.Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science.- Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications- Contributions from international leaders provide insight into background and future understanding for clinical and translational science- Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health.

This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science.

Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health.This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science.- Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine- Brings insights from international leaders into the discipline of clinical and translational science- Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

There have been few studies of the Law Lords, and no study of them by a political scientist for more than ten years. This book concentrates on the arguments the Law Lords use in justifying their decisions, and is concerned as much with the legal methodology as with the substance of their decisions. Very close attention is paid to the different approaches and styles of judicial argument, but the book is not restricted to this traditional analytic approach. One chapter applies the statistical techniques Americans call 'jurimetrics' and have successfully used on the US Supreme Court. The main theme is that the Law Lords enjoy and fully utilise far more discretion in their judgements than is normally admitted, and that much depends on exactly which judges happen to hear a case. the second part of the book shows the impact this extreme discretion has had in shaping both public law and areas of civil law.

What were the Founding Fathers really thinking when they gathered in the Pennsylvania State House to draft the United States Constitution? When answering this question, most have relied on The Federalist Papers, which was first published in book form after the close of the Convention, in 1788. To this day, the book's status is sacrosanct for most Americans. Yet as David Brian Robertson shows, the Papers represented one side of the debate and does not fully capture the political sensibilities that produced the U.S. Constitution. Robertson, drawing from the full range of contemporary sources and not just the Papers, provides a truly authoritative account of the founders' collective political reasoning during the Convention. Organized thematically, each chapter covers a crucial Constitutional issue: the respective roles of the executive, the judiciary, and the legislature; the balance between the federal government and the states; slavery; and war and peace. In virtually every instance, the process was decidedly political, fractious, and piecemeal. As much as they wanted to design the government that would best serve their people, the Founders struggled to balance their broad ideals with self-interested policies and procedures. Robertson's boldly revisionist account of the political horse-trading that dominated the Convention not only greatly enriches our understanding of the nation's founding; it also elucidates why the government they created has proven so difficult to use.

The eighty-five famous essays by Hamilton, Madison, and Jay--known collectively as the Federalist Papers--comprise the lens through which we typically view the ideas behind the U.S. Constitution. But we are wrong to do so, writes David Brian Robertson, if we really want to know what the Founders were thinking. In this provocative new account of the framing of the Constitution, Robertson observes that the Federalist Papers represented only one side in a fierce argument that was settled by compromise--in fact, multiple compromises. Drawing on numerous primary sources, Robertson unravels the highly political dynamics that shaped the document. Hamilton and Madison, who hailed from two of the larger states, pursued an ambitious vision of a robust government with broad power. Leaders from smaller states envisioned only a few added powers, sufficient to correct the disastrous weakness of the Articles of Confederation, but not so strong as to threaten the governing systems within their own states. The two sides battled for three arduous months; the Constitution emerged piece by piece, the product of an evolving web of agreements. Robertson examines each contentious debate, including arguments over the balance between the federal government and the states, slavery, war and peace, and much more. In nearly every case, a fractious, piecemeal, and very political process prevailed. In this way, the convention produced a government of separate institutions, each with the will and ability to defend its independence. Majorities would rule, but the Constitution made it very difficult to assemble majorities large enough to let the government act. Brilliantly argued and deeply researched, this book will change the way we think of "original intent." With a bracing willingness to challenge old pieties, Robertson rescues the political realities that created the government we know today.

The eighty-five famous essays by Hamilton, Madison, and Jay--known collectively as the Federalist Papers--comprise the lens through which we typically view the ideas behind the U.S. Constitution. But we are wrong to do so, writes David Brian Robertson, if we really want to know what the Founders were thinking. In this provocative new account of the framing of the Constitution, Robertson observes that the Federalist Papers represented only one side in a fierce argument that was settled by compromise--in fact, multiple compromises. Drawing on numerous primary sources, Robertson unravels the highly political dynamics that shaped the document. Hamilton and Madison, who hailed from two of the larger states, pursued an ambitious vision of a robust government with broad power. Leaders from smaller states envisioned only a few added powers, sufficient to correct the disastrous weakness of the Articles of Confederation, but not so strong as to threaten the governing systems within their own states. The two sides battled for three arduous months; the Constitution emerged piece by piece, the product of an evolving web of agreements. Robertson examines each contentious debate, including arguments over the balance between the federal government and the states, slavery, war and peace, and much more. In nearly every case, a fractious, piecemeal, and very political process prevailed. In this way, the convention produced a government of separate institutions, each with the will and ability to defend its independence. Majorities would rule, but the Constitution made it very difficult to assemble majorities large enough to let the government act. Brilliantly argued and deeply researched, this book will change the way we think of "original intent." With a bracing willingness to challenge old pieties, Robertson rescues the political realities that created the government we know today.

Although the authors believe that the level of conventional and nuclear forces in Europe should and will be reduced, they do not consider that the military instrument will have lost all of its value in European political affairs. They still see a need to be prepared for tension and conflict.

This master politician and self-made man served for half a century, as congressman and later as key New Deal senator from his native South Carolina; as Supreme Court justice; as "assistant president" during the Second World War; as Truman's secretary of state in the early years of the Cold War; and, finally, as governor of South Carolina. He came tantalisingly close to the American presidency and was a key participant in the decision to drop the atomic bomb on Japan. In later years he was a seminal figure in the so-called Southern Strategy that brought Richard Nixon to the White House. For his shrewdness and mastery of the art of politics Byrnes earned the sobriquet "sly and able." He was surely both--and one of the key shapers of American politics in this century.

This dictionary is the essential guide to politics, its terminologies, ideologies and institutions. Providing authoritative and up-to-date information that is invaluable to both students and general readers, it includes:well over 500 extensive definitionsan understanding of the basics of political thought and theoryclear, no-nonsense coverage of complex ideologies and dogmassuccinct definitions of highly specialized and technical terms.Previously published by Penguin, this third edition has been extensively revised and updated with many new entries.

The relevance of this book to central concerns of political and social science hardly needs emphasizing. Parties are the organizing force of democratic governments, giving coherence and direction to their policies and relating them to popular preferences. Election programmes are crucial to this role, providing electors with some insight into the policies they are voting for, and parties themselves with a starting point for their activity in government. Discussion begins with a comparative assessment of the impact of election pledges on government action. The book goes on to describe systematically the place of the programmes in the political process of nineteen democracies. It subjects them to detailed qualitative, quantitative and spatial analyses to answer such questions as: Who prepares election programmes and how? What is the nature of modern party divisions? Do they differ across countries? Is there indeed an 'end of ideology' or an intensification? Does the need to attract votes weaken old partisan attachments? Combining individual studies of each country with comparative analyses on a scale never previously undertaken, the book will interest country specialists and comparativists and prove indispensable to research on voting and party behaviour, coalition formation, ideology, and rational choice.

The relevance of this book to central concerns of political and social science hardly needs emphasizing. Parties are the organizing force of democratic governments, giving coherence and direction to their policies and relating them to popular preferences. Election programmes are crucial to this role, providing electors with some insight into the policies they are voting for, and parties themselves with a starting point for their activity in government. Discussion begins with a comparative assessment of the impact of election pledges on government action. The book goes on to describe systematically the place of the programmes in the political process of nineteen democracies. It subjects them to detailed qualitative, quantitative and spatial analyses to answer such questions as: Who prepares election programmes and how? What is the nature of modern party divisions? Do they differ across countries? Is there indeed an 'end of ideology' or an intensification? Does the need to attract votes weaken old partisan attachments? Combining individual studies of each country with comparative analyses on a scale never previously undertaken, the book will interest country specialists and comparativists and prove indispensable to research on voting and party behaviour, coalition formation, ideology, and rational choice.

This volume provides a comprehensive assessment of the likely effects of the Uruguay Round agreements on the dynamic economies of East Asia. The rapid development of these countries owes much to the strong export performance and unilateral deregulation of their economies in recent years. Their major stake in maintaining the integrity of the global trading system was demonstrated by their active participation in the negotiations. The impact of the Uruguay Round liberalisation on East Asian economic development and policies is evaluated using sophisticated CGE models to estimate the effects on trade and income. The strengthening of trade rules and dispute settlement procedures are examined by a group of world trade experts. They establish that some gaps in the system remain to be tackled (anti-dumping, regional discrimination) and that some new problems are pending (competition policy, investment).

The Judge as Political Theorist examines opinions by constitutional courts in liberal democracies to better understand the logic and nature of constitutional review. David Robertson argues that the constitutional judge's role is nothing like that of the legislator or chief executive, or even the ordinary judge. Rather, constitutional judges spell out to society the implications--on the ground--of the moral and practical commitments embodied in the nation's constitution. Constitutional review, in other words, is a form of applied political theory. Robertson takes an in-depth look at constitutional decision making in Germany, France, the Czech Republic, Poland, Hungary, Canada, and South Africa, with comparisons throughout to the United States, where constitutional review originated. He also tackles perhaps the most vexing problem in constitutional law today--how and when to limit the rights of citizens in order to govern. As traditional institutions of moral authority have lost power, constitutional judges have stepped into the breach, radically altering traditional understandings of what courts can and should do.Robertson demonstrates how constitutions are more than mere founding documents laying down the law of the land, but increasingly have become statements of the values and principles a society seeks to embody. Constitutional judges, in turn, see it as their mission to transform those values into political practice and push for state and society to live up to their ideals.

Norfolk has a wealth of important archaeological sites, historic buildings and landscapes. This guide is the first to use them to tell the county’s rich history.Starting with real footprints of people who lived here nearly 1 million years ago, A History of Norfolk in 100 Places will take you on a chronological journey through prehistoric monuments, Roman forts, medieval churches and Nelson’s Monument, right up to twentieth-century defensive sites. With detailed entries illustrated by aerial photographs and ground-level shots, here you will find a reliable guide to historic places that are either open to the public, or are visible from public roads or footpaths for you to explore.

During the late Hellenistic and early Imperial periods (B.C. 50 - A.D. 300), important developments may be traced in the philosophy of language and its relationship to mind. This book examines theories of language in the work of theologians and philosophers linked to Ancient Alexandria. The growth of Judaism and Christianity in cultural centers of the Roman Empire, above all Alexandria, provides valuable testimony to the philosophical vitality of this period. The study of Later Greek philosophy should be more closely integrated with the Church Fathers, particularly in the theologically sensitive issue of the nature of language. Robertson traces some related attempts to reconcile immaterial, intelligible reality and the intelligibility of language, explain the structure of language, and clarify the nature of meaning. These shared problems are handled with greater philosophical sophistication by Plotinus, although the comparison with Philo, Clement, and Origen illustrates significant similarities as well as differences between Neoplatonism and early Jewish and Christian philosophy.

This study of CAMI Automotive, a unionized joint venture between General Motors and Suzuki, is the most comprehensive ever undertaken of a lean production plant. James Rinehart, Christopher Huxley, and David Robertson address a topic that has inspired fierce debate in industrial relations, sociology, labor studies, and human resource management. Heralded as a model of lean production when it opened in 1989, CAMI promised workers something different from traditional plants—a humane environment, empowerment, and cooperative labor-management relations. However, the enthusiasm workers felt during the orientation and early phases of production steadily declined, as did their involvement in participatory activities. Workers came to describe CAMI as "just another car factory." Union challenges and shopfloor resistance to key elements of the lean system grew, capped by a five-week strike in 1992. The authors attribute workers' disillusionment to lean production itself rather than to North American managers' inadequate implementation.

This study of CAMI Automotive, a unionized joint venture between General Motors and Suzuki, is the most comprehensive ever undertaken of a lean production plant. James Rinehart, Christopher Huxley, and David Robertson address a topic that has inspired fierce debate in industrial relations, sociology, labor studies, and human resource management. Heralded as a model of lean production when it opened in 1989, CAMI promised workers something different from traditional plants—a humane environment, empowerment, and cooperative labor-management relations. However, the enthusiasm workers felt during the orientation and early phases of production steadily declined, as did their involvement in participatory activities. Workers came to describe CAMI as "just another car factory." Union challenges and shopfloor resistance to key elements of the lean system grew, capped by a five-week strike in 1992. The authors attribute workers' disillusionment to lean production itself rather than to North American managers' inadequate implementation.

David Robertson charts W. C. Handy's rise from a rural-Alabama childhood in the last decades of the nineteenth century to his emergence as one of the most celebrated songwriters of the twentieth century. The child of former slaves, Handy was first inspired by spirituals and folk songs, and his passion for music pushed him to leave home as a teenager, despite opposition from his preacher father. Handy soon found his way to St. Louis, where he spent a winter sleeping on cobblestone docks before lucking into a job with an Indiana brass band. It was in a minstrel show, playing to racially mixed audiences across the country, that he got his first real exposure as a professional musician, but it was in Memphis, where he settled in 1905, that he hit his full stride as a composer. At once a testament to the power of song and a chronicle of race and black music in America, W. C. Handy's life story is in many ways the story of the birth of our country's indigenous culture - and a riveting must read for anyone interested in the history of American music.

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David Robertson charts W. C. Handy’s rise from a rural-Alabama childhood in the last decades of the nineteenth century to his emergence as one of the most celebrated songwriters of the twentieth century. The child of former slaves, Handy was first inspired by spirituals and folk songs, and his passion for music pushed him to leave home as a teenager, despite opposition from his preacher father. Handy soon found his way to St. Louis, where he spent a winter sleeping on cobblestone docks before lucking into a job with an Indiana brass band. It was in a minstrel show, playing to racially mixed audiences across the country, that he got his first real exposure as a professional musician, but it was in Memphis, where he settled in 1905, that he hit his full stride as a composer. At once a testament to the power of song and a chronicle of race and black music in America, W. C. Handy’s life story is in many ways the story of the birth of our country’s indigenous culture—and a riveting must read for anyone interested in the history of American music.