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The papers contained in this volumewere presented at the 11thAnnual Sym- sium on CombinatorialPattern Matching, held June 21-23, 2000 at the Univ- sit edeMontr eal. They were selected from 44 abstracts submitted in response to the call for papers. In addition, there were invited lectures by Andrei Broder (AltaVista), Fernando Pereira (AT&T Research Labs), and Ian H. Witten (U- versity of Waikato). The symposium was preceded by a two-day summer school set up to - tract and train young researchers. The lecturers at the school were Greg Butler, ClementLam,andGusGrahne:BLAST!Howdoyousearchsequencedatabases?, DavidBryant:Phylogeny,Ra aeleGiancarlo: Algorithmicaspectsof speech rec- nition, Nadia El-Mabrouk: Genome rearrangement,LaxmiParida: Flexib- pattern discovery, and Ian H. Witten: Adaptive text mining: inferring structure from sequences. Combinatorial Pattern Matching (CPM) addresses issues of searching and matching strings and more complicated patterns such as trees, regular expr- sions graphs, point sets, and arrays.The goal is to derive non-trivial combi- torial properties of such structures and to exploit these properties in order to achieve superior performance for the corresponding computational problems. Over recent years a steady ?ow of high-quality research on this subject has changed a sparse set of isolated results into a fully-?edged area of algorithmics. - Del 5 - SERIES ON ADVANCES IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY
PROCEEDINGS OF THE 5TH ASIA-PACIFIC BIOINFORMATICS CONFERENCE
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High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, and gene expression profiles of normal and diseased tissues are being rapidly generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industrial practitioners at the 5th Asia-Pacific Bioinformatics Conference held in Hong Kong in January 2007.Sample Chapter(s)
