Derek Wakelin – författare

Edited by F.E.G. Cox, Derek Wakelin, Stephen H. Gillespie and Dickson D. Despommier. Parasitic infections present a major challenge to the health and well being of several billions of people across the world. Political unrest, natural disasters, the migrations of huge populations and the spread of HIV infections have added to already serious problems by increasing global parasite burdens. Increasingly it is becoming clear that interactions between parasites and other infectious agents can aggravate disease. Against this backdrop, progress is being made in the containment of many parasitic infections and there is optimism that some of the diseases that have plagued humans for centuries may be eradicated. Hopes for the future revolve around the application of modern molecular, genetic and immunological science, linked to the systematic use of evidence-based control methods. All these themes and more run through the chapters in this volume. Parasitology has been thoroughly revised and updated for the tenth edition of Topley & Wilson’s Microbiology and Microbial Infections to include all newly identified parasites and emerging diseases. Through discussion of the general aspects of parasitology and detailed reviews of specific organisms (grouped under protozoa and helminths) the volume provides an authoritative survey of current knowledge of parasitic organisms and the human diseases to which they give rise, what their effects are and ways in which they can be controlled, not only now, but also in the future. The comprehensive coverage includes the basic science that underlies disease transmission and progression, the classification and identification of the organisms concerned, and the epidemiology and treatment of the diseases caused. Parasitology is an invaluable companion for infectious disease specialists, pathologists, parasitologists and all others working in this increasingly important field.

Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.