Dhruba Kumar Bhattacharyya – författare

Development of high-throughput technologies in molecular biology during the last two decades has contributed to the production of tremendous amounts of data. Microarray and RNA sequencing are two such widely used high-throughput technologies for simultaneously monitoring the expression patterns of thousands of genes. Data produced from such experiments are voluminous (both in dimensionality and numbers of instances) and evolving in nature. Analysis of huge amounts of data toward the identification of interesting patterns that are relevant for a given biological question requires high-performance computational infrastructure as well as efficient machine learning algorithms. Cross-communication of ideas between biologists and computer scientists remains a big challenge.

Gene Expression Data Analysis: A Statistical and Machine Learning Perspective has been written with a multidisciplinary audience in mind. The book discusses gene expression data analysis from molecular biology, machine learning, and statistical perspectives. Readers will be able to acquire both theoretical and practical knowledge of methods for identifying novel patterns of high biological significance. To measure the effectiveness of such algorithms, we discuss statistical and biological performance metrics that can be used in real life or in a simulated environment. This book discusses a large number of benchmark algorithms, tools, systems, and repositories that are commonly used in analyzing gene expression data and validating results. This book will benefit students, researchers, and practitioners in biology, medicine, and computer science by enabling them to acquire in-depth knowledge in statistical and machine-learning-based methods for analyzing gene expression data.

Key Features:

Development of high-throughput technologies in molecular biology during the last two decades has contributed to the production of tremendous amounts of data. Microarray and RNA sequencing are two such widely used high-throughput technologies for simultaneously monitoring the expression patterns of thousands of genes. Data produced from such experiments are voluminous (both in dimensionality and numbers of instances) and evolving in nature. Analysis of huge amounts of data toward the identification of interesting patterns that are relevant for a given biological question requires high-performance computational infrastructure as well as efficient machine learning algorithms. Cross-communication of ideas between biologists and computer scientists remains a big challenge.

Gene Expression Data Analysis: A Statistical and Machine Learning Perspective has been written with a multidisciplinary audience in mind. The book discusses gene expression data analysis from molecular biology, machine learning, and statistical perspectives. Readers will be able to acquire both theoretical and practical knowledge of methods for identifying novel patterns of high biological significance. To measure the effectiveness of such algorithms, we discuss statistical and biological performance metrics that can be used in real life or in a simulated environment. This book discusses a large number of benchmark algorithms, tools, systems, and repositories that are commonly used in analyzing gene expression data and validating results. This book will benefit students, researchers, and practitioners in biology, medicine, and computer science by enabling them to acquire in-depth knowledge in statistical and machine-learning-based methods for analyzing gene expression data.

Key Features:

DDoS Attacks: Evolution, Detection, Prevention, Reaction, and Tolerance discusses the evolution of distributed denial-of-service (DDoS) attacks, how to detect a DDoS attack when one is mounted, how to prevent such attacks from taking place, and how to react when a DDoS attack is in progress, with the goal of tolerating the attack. It introduces types and characteristics of DDoS attacks, reasons why such attacks are often successful, what aspects of the network infrastructure are usual targets, and methods used to launch attacks.

The book elaborates upon the emerging botnet technology, current trends in the evolution and use of botnet technology, its role in facilitating the launching of DDoS attacks, and challenges in countering the role of botnets in the proliferation of DDoS attacks. It introduces statistical and machine learning methods applied in the detection and prevention of DDoS attacks in order to provide a clear understanding of the state of the art. It presents DDoS reaction and tolerance mechanisms with a view to studying their effectiveness in protecting network resources without compromising the quality of services.

To practically understand how attackers plan and mount DDoS attacks, the authors discuss the development of a testbed that can be used to perform experiments such as attack launching, monitoring of network traffic, and detection of attacks, as well as for testing strategies for prevention, reaction, and mitigation. Finally, the authors address current issues and challenges that need to be overcome to provide even better defense against DDoS attacks.

The two-volume set of LNCS 11941 and 11942 constitutes the refereed proceedings of the 8th International Conference on Pattern Recognition and Machine Intelligence, PReMI 2019, held in Tezpur, India, in December 2019.

The 131 revised full papers presented were carefully reviewed and selected from 341 submissions. They are organized in topical sections named: Pattern Recognition; Machine Learning; Deep Learning; Soft and Evolutionary Computing; Image Processing; Medical Image Processing; Bioinformatics and Biomedical Signal Processing; Information Retrieval; Remote Sensing; Signal and Video Processing; and Smart and Intelligent Sensors.