Dileep Kumar - Böcker

Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.Provides valuable insights into optimizing patient outcomes and improving clinical practicesOffers a nuanced understanding of breast cancer biology, epidemiology, and therapeutic innovations, stimulating further academic exploration and inquiryElucidates the evolving landscape of oncology research, guiding industry efforts towards more effective and targeted therapies

Chemoresistance in Glioblastoma: Understanding and Management gives clear insights into the detailed characteristic aspects of glioblastoma disease and the different therapeutic targets that are employed in reducing resistance to chemotherapeutic agents. The book delves deep into the root causes of multidrug resistance and the quest for novel molecular targets among growth factors, receptors, signal transduction proteins, microRNAs, transcription factors, proto-oncogenes, and tumor suppressor genes. In addition, it gives insights on the pathological and molecular features of glioblastoma and the role of cancer stem cells in the resistance to chemo and immunotherapy.While designed as a comprehensive guide, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within chemoresistance.Offers practical guidance for diagnosing and treating chemoresistance in glioblastomaProvides evidence-based information to formulate effective strategies for chemoresistance in glioblastomaGives a comprehensive overview of the phenomenon of multidrug resistance in glioblastomas

Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.Provides a comprehensive examination of Apolipoprotein E (ApoE) in various health conditions and diseases, including cardiovascular diseases, Alzheimer's, neurological disorders, and cancerDelivers detailed insights into the genetic variability of ApoE, explaining how different genotypes influence disease risk and therapeutic responsesIntegrates perspectives from biochemistry, molecular biology, genetics, neurology, and cardiology to offer a holistic understanding of ApoEHighlights the pharmacogenetics of ApoE, illustrating its potential in personalized medicine and targeted therapeutic strategies

This book comprehensively explores the latest advancements in the understanding, diagnosis, and treatment of neurodegenerative diseases. The chapters provide an in-depth review of current approaches and treatment strategies for Alzheimer's disease, offering insights into the latest developments and breakthroughs. It also reviews the cutting-edge research on potential novel targets for Alzheimer's pharmacotherapy, with a focus on JNK3, GSK3β, and Fyn kinase inhibitors, providing an update on related approaches and their implications. It discusses the potential of ethnomedicines as a promising tool for mitigating Alzheimer's disease, offering insights into traditional remedies and their modern applications. Additional chapters explore the influence of microglia, the neuropharmacological mechanisms associated with SARS-CoV-2, and the molecular intricacies of Parkinson’s disease. The book further covers the evolving role of artificial intelligence and machine learning in the management of neurodegenerative disorders. The chapters also examine the role of nanotechnology in addressing the challenges of diseases like multiple sclerosis. Towards the end, the book examines the role of oxidative damage in neurodegeneration and its management in related disorders. This book is an important source for neuroscientists, neurologists, and students of neuroscience.

Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and regulation mechanisms to its deficiency and its implications in related disorders.

This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.