Divya Vohora – författare

Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features.As a greater understanding of these aspects is critical for students in the areas of pharmaceutical medicine, clinical research, pharmacology and pharmacy, as well as professionals working in the pharmaceutical industry, this book is an ideal resource. Includes detailed coverage of current trends and key topics in pharmaceutical medicine, including biosimilars, biobetters, super generics, and Provides a comprehensive look at current and important aspects of the science and regulation of drug and biologics discovery

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and DisordersThe H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer’s disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the last two decades. It brings together an elite group of 30 pioneering researchers. In writing about their own work, these scientists report on the cutting-edge investigations that are now being conducted across a variety of disciplines. This text is designed to aid researchers and inform those involved in the treatment and clinical aspects of a number of histamine-related diseases.Presents Several Disease-Specific ChaptersCertainly, the most comprehensive and cutting-edge volume in the field, this text includes material drawn from groundbreaking research techniques and patent literature. Put together with great thought and passion, it is written to serve as a primary resource for anyone involved with or interested in the identification and localization of H3 receptors and the ligands being developed as therapeutic agents to treat a wide range of diseases including some that were once considered intractable.

This book provides a comprehensive overview of the emerging field of senotherapeutics and its potential applications in various diseases. The initial chapter elucidates the central role of cellular senescence and the senescence-associated secretory phenotype (SASP) in the intricate balance between health and disease. The subsequent chapter examines the origin of senotherapeutics, introducing the concepts of senolytics and senomorphics for combating senescence and its associated disorders. The book also focuses on the potential of senotherapeutics in managing neurological disorders and neurodegenerative diseases. Furthermore, it investigates the intersection of senotherapeutics with cancer therapy, shedding light on innovative treatments and their role against cancer. It also discusses the broader role of senotherapeutics in aging and its associated disorders such as osteoporosis and osteoarthritis, offering insights into their implications for geriatric medicine. The book reviews the novel application of senotherapeutics in skincare and dermatological diseases, as well as metabolic disorders. This book is intended for researchers in the fields of biomedicine, pharmacology, and gerontology, as well as healthcare professionals.Key FeaturesOffers a comprehensive exploration of senotherapeutics, spanning various diseases and conditions, providing a holistic understanding of its potential applications.Provides a conceptual framework for cellular senescence and the senescence-associated secretory phenotype (SASP) and their relevance to health and disease.Examines the potential of senotherapeutics in addressing neurological disorders, neurodegenerative diseases, and cancer therapy.Explores the broader role of senotherapeutics in the context of aging and associated disorders such as osteoarthritis and osteoporosis.Reviews the application of senotherapeutics in skincare and dermatological concerns, as well as metabolic disorders.

Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use of medicinal plants. It stands out from other books by directing your attention to the aspects of safety and toxicity.The authors venture into the relatively unexplored (or deliberately hidden) side of the picture. They present a survey of approximately 1500 medicinal plants and herbal products, 59 global (from 27 countries) and 75 Indian examples of toxic and adverse effects and drug interactions. Additionally, they present the current status of regulatory laws and their enforcement in 73 countries to support their contention that such laws and enforcement are inadequate, and that herbal drugs are unscientifically being promoted as totally safe.To give you the full picture, the authors go on to examine such issues as danger from large-scale misuse and abuse, self-prescription, substitution, adulteration, concurrent use with modern medicines, hazardous but avoidable drug interactions, risk groups, and present status of drug regulations.

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research.

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research.

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and DisordersThe H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer’s disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the last two decades. It brings together an elite group of 30 pioneering researchers. In writing about their own work, these scientists report on the cutting-edge investigations that are now being conducted across a variety of disciplines. This text is designed to aid researchers and inform those involved in the treatment and clinical aspects of a number of histamine-related diseases.Presents Several Disease-Specific ChaptersCertainly, the most comprehensive and cutting-edge volume in the field, this text includes material drawn from groundbreaking research techniques and patent literature. Put together with great thought and passion, it is written to serve as a primary resource for anyone involved with or interested in the identification and localization of H3 receptors and the ligands being developed as therapeutic agents to treat a wide range of diseases including some that were once considered intractable.

Are herbal drugs totally devoid of adverse effects when used alone, as herbal formulations, or in concurrent use with modern medicines? Safety Concerns for Herbal Drugs examines that question and others like it to give you the information you need to judge for yourself the balance between the risks and benefits associated with the therapeutic use of medicinal plants. It stands out from other books by directing your attention to the aspects of safety and toxicity.The authors venture into the relatively unexplored (or deliberately hidden) side of the picture. They present a survey of approximately 1500 medicinal plants and herbal products, 59 global (from 27 countries) and 75 Indian examples of toxic and adverse effects and drug interactions. Additionally, they present the current status of regulatory laws and their enforcement in 73 countries to support their contention that such laws and enforcement are inadequate, and that herbal drugs are unscientifically being promoted as totally safe.To give you the full picture, the authors go on to examine such issues as danger from large-scale misuse and abuse, self-prescription, substitution, adulteration, concurrent use with modern medicines, hazardous but avoidable drug interactions, risk groups, and present status of drug regulations.

The book delves into the intricate interplay of stress and adaptive responses, and their multifaceted dynamics influenced by stress type, exposure duration, genetic factors, and lifestyle elements.