Eduardo Bruera – författare

50 Studies Every Palliative Care Doctor Should Know presents key studies that have shaped the practice of palliative medicine. Selected using a rigorous methodology, the studies cover topics including: palliative care, symptom assessment and management, psychosocial aspects of care and communication, and end-of-life care. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

Gastrointestinal symptoms such as anorexia-cachexia, chronic nausea, vomiting and bowel obstruction are highly distressing for patients with advanced cancer. Approximately one in three adults will be diagnosed with cancer in their lives and approximately fifty per cent of them will die because of malignancy. More than eighty per cent of patients who die of cancer will present severe gastrointestinal symptoms before death.This book presents detailed, evidence-based information on each of the gastrointestinal symptoms for a multi-disciplinary audience. Comprehensive guidelines have been included on how to assess the patient, in order to ensure effective treatment, in which prescribing is tailored to the cause of the symptoms and to the patient's individual needs. The book recognises that the aim of good cancer management and palliative care is to assess, diagnose, manage and treat these symptoms to ensure best quality of life.

Palliative and end-of-life care are concerned with the physical, social, psychological, and spiritual care of people with advanced disease and serious illness. They affect people in all societies, all countries, and are growing fields post-Covid. Changing demographics and treatments mean that people are living longer with serious illness and multiple conditions, often needing symptom control and complex care and support. Research in these areas present a particular challenge, both because of the ethical and practical difficulties inherent in working with very ill patients and their families, and because of the range of research questions considered to be within the domain of palliative care.Building on the first edition, this book provides an introduction to research methods in the fields of palliative, supportive, and end-of-life care, and complex patients. Edited by six experienced palliative care academics with acknowledged expertise and international reputations in this field, this book is both authoritative and accessible. It encompasses methods used in both clinical and health services research, covering methodological theory, design, measures, and practice and case examples across the entire scope of research. The book has been fully updated and includes the latest developments such as use of big data and forming research collaborations.This will be an essential methodological book for clinicians, academics, researchers and educators, and especially those undertaking a MSc, PhD, or early career researchers in palliative care and related fields.

Palliative care, which focuses on the management of phenomena that produce discomfort and otherwise undermine the quality of life of patients with incurable medical disorders, is a clinical specialty that is just beginning to define itself in the United States. This first volume in the Topics in Palliative Care series will discuss palliative care topics, such as pharmacotherapy of pain, adjustments to cancer, management of delirium, and gastrointestinal disorders.

The rapidly evolving field of Palliative Care focuses on the management of phenomena that produce discomfort and that undermine the quality of life of patients with incurable medical disorders. The interdisciplinary clinical purview includes those factors - physical, psychological, social, and spiritual - that contribute to suffering, undermine quality of life, and prevent a death with comfort and dignity. Palliative Care is a fundamental part of clinical practice, the "parallel universe" to therapies directed at cure or prolongation of life. All clinicians who treat patients with chronic life-threatening diseases are ingaged in palliative care, continually attempting to manage complex symptomatology and functional disturbances.The scientific foundation of palliative care is advancing, and similarly, methods are needed to highlight, for practitioners at the bedside, the findings of empirical research. TOPICS IN PALLIATIVE CARE has been designed to meet the need for enhanced communication in this field.To highlight the diversity of concerns in palliative care, each volume of the TOPICS IN PALLIATIVE CARE Series is divided into sections that address a range of issues. Addressing aspects of symptom control, psychosocial functioning, spiritual or existential concerns, ethics, and other topics, the chapters in each section review the given area and focus on a small number of salient issues to analysis. The authors present and evaluate existing data, provide a context drawn from both the clinical and research settings, and intergrate knowledge in a manner that is both practical and readable. The specific topics covered in Volume 2 are Neuropathic Pain, Cachexia/Anorexia, Asthenia, and Psychological Issues in the Caregiver.

The third book in a series devoted to research and practice in palliative care. The four topics covered in this volume are Paediatric Palliative Care, The Management of Bone Pain, Psychopathology in Patients with Cancer, Skin Disorders and Their Management. The contributors present and evaluate existing data, provide a context drawn from both clinical and research settings, and integrate knowledge in a manner that is both practical and readable for palliative care specialists and hospice providers.

Palliative care is rapidly evolving as a multidimensional therapeutic model devoted to improving the quality of life of all patients with life-threatening illness. Symptom control, management of psychosocial and spiritual concerns, decision making consistent with values and goals, and care of the imminently dying that is appropriate and sensitive to the unique needs of the individual and family - these are among the critical issues addressed through palliative care. As this discipline has evolved, the need for research in all these areas has become widely acknowledged. Issues in Palliative Care Research describes both the progress that already has been made in the investigation of these issues and the methodological elements that must be addressed in future studies. The perspective is broad and the overriding goal is to inform about the state of the art in these rapidly evolving areas of research.

This is the fourth book in a series devoted to research and practice in palliative care. This rapidly evolving field focuses on the management of phenomena that produce discomfort and undermine the quality of life of patients with incurable medical disorders. To highlight the diversity in this field, each volume is divided into sections that address a range of issues. Various sections discuss aspects of symptom control, psychosocial functioning, spiritual orr existential concerns, ethics, and other topics. The four sections in this volume are; Survival Estimation in Palliative Care, Education and Training in Palliative Care, Procoagulant and Anticoagulant Therapy in Palliative Care, and Issues in the Assessment and Management of Common Symptoms. The authors present and evaluate existing data, provide a context drawn from both the clinic and research, and integrate knowledge in a manner that is both practical and readable.

The rapidly evolving field of Palliative Care focuses on the management of phenomena that produce discomfort and that undermine the quality of life of patients with incurable medical disorders. The interdisciplinary clinical purview includes those factors - physical, psychological, social, and spiritual - that contribute to suffering, undermine the quality of life, and prevent a death with comfort and dignity. Palliative Care is a fundamental part of clinical practice, the "parallel universe" to therapies directed at cure or prolongation of life. All clinicians who treat patients with chronic life threatening diseases are engaged in palliative care, continually attempting to manage complex symptomatology and functional disturbances. The scientific foundation of palliative care is advancing, and similarly, methods are needed to highlight, for practioners at the bedside, the findings of empirical research. Topics in Palliative Care Series is divided into sections that address a range of issues. Addressing aspects of sumptom control, psyshocsoical functioning, spiritual or existential concerns, ethics, and other topics, the chapters in each section review the given area and focus on a small number of salient issues for analysis. The authors present and evaluate existing data, provide a context drawn from clinical and research settings, and integrate knowledge in a manner that is both practical and readable. The specific topics covered in Volume 5 are Cultural issues in Palliative Care, Palliative Care in Geriatrics, Communication Issues in Palliative Care, Outcomes Research in Palliative Care, Opiod Tolerance; Reality of Myth?, and Pain and other symptoms: Treatment Challenges.

50 Pharmacotherapy Studies Every Palliative Practitioner Should Know is a compilation of key pharmacotherapy studies that form the foundation of evidence-based practice. The studies cover topics including: agitation and delirium, fatigue, nausea and vomiting, pain, anorexia and cachexia, ALS, seizure, dyspnea, anxiety, pruritis, symptom clusters, COPD, cancer, and more. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case offers readers the opportunity to conceptualize findings. As with all books in the "50 Studies" series, each study was selected using an objective selection criterion that included citations per year, high levels of evidence, clinical studies and trials, and a 3-stage Delphi review by international experts in the field. This book is a must-read for palliative practitioners, pharmacists, advance practice nurses, and physician assistants, and anyone who wants to learn more about the data behind clinical practice.

This is the second book in a new international, multi-contributed series aimed at providing practical, clinical guidance on how to deal with difficult symptoms related to specific cancer sites. In gynaeoncology there are a number of symptoms which cause great distress to the individual and their families, and perplexity to the physicians and nurses caring for them. This volume covers the management of incurable disease for each of the most common cancers followed by a review of the most difficult symptoms that are encountered in this tumour group. Contributors provide a scientific background to symptom-control chapters, with an indication of the sources and evidence for their advice.

This is the third book in a new international, multi-contributed series aimed at providing practical, clinical guidance on how to deal with difficult symptoms related to specific cancer sites. There are few more distressing problems for patients and families than the development of a primary or secondary brain tumour. Treatment is often palliative, though intensive, from the start. Little firm evidence exists to guide the physician in caring for patients with seizures refractory to standard treatment. Most of the work is based on case reports or personal experience. This book draws the information together in an easily accessible form so that the book can be read and referred to on the ward, or before a domiciliary visit.Specialists in palliative care and oncology settings, working in the acute sector and in hospices, will find this book invaluable. It will also appeal to consultants as well as specialist registrars, clinical nurse specialists and nurse practitioners in palliative care, oncology and neurology.

Palliative Care Consultations in Haemato-oncology is the first book in a new international, multi-contributed series aimed at providing practical, clinical guidance on how to deal with difficult symptoms related to specific cancer sites. Patients with haematological malignancy often undergo the most rigorous treatments, usually requiring long inpatient stays at tertiary referral centres far removed from friends, families and everyday life. The treatment for some malignancies is palliative, although aggressive, from diagnosis and there can be a number of difficult symptom-control problems all of which are covered in this book. This volume draws on the expertise of the haematologist who is vital if the patient is to have optimal care and provides practical advice in an easily accessible form so that the book can be read and referred to on the ward, or before a domiciliary visit.

Palliative and end of life care are concerned with the physical, social, psychological and spiritual care of people with advanced disease. It currently has a poorly developed research base, but the need to improve this is increasingly recognised. One of the reasons for the lack of research - and the variable quality of the research that is undertaken - is the difficulty of conducting research with very ill and bereaved people. Standard and well-established research methods may need to be adapted to work in this context. This means that existing research methods textbooks may be of limited use to palliative care practitioners seeking to do research for the first time, or to more experienced researchers wanting to apply their knowledge in palliative care settings. This research methods textbook is the first to be written specifically for palliative care. It has been edited by four experienced palliative care academics with acknowledged expertise and international reputations in this field. It encompasses methods used in both clinical and health services research in palliative care, with sections on clinical, epidemiological, survey and qualitative research, as well as a section covering skills needed in any research project. Each chapter provides readers with an up to date overview of the research method in question, an understanding of its applicability to palliative care and of the particular challenges of using it in this setting. It is essential reading for all palliative care researchers.

Patients with advanced cancer may develop a number of clinical complications related to tumor progression or a variety of aggressive treatments. The majority of these patients are elderly, often with multiple co-morbidities that require appropriate assessment and management. In the palliative stage of their disease, patients undergo a progressive transition from active acute care to community-based hospice care. This transition requires modification in the diagnostic tests, monitoring procedures and pharmacological treatments to adjust them to the palliative and short-term nature of the care. Internal Medicine Issues in Palliative Cancer Care looks at internal medicine through a prognosis-based framework and provides a practical approach to maximizing comfort and quality of life while minimizing aggressive investigations and therapies for patients with life-limiting disease. Forty-six common internal medicine conditions are organized into nine clinical categories: pulmonary, cardiovascular, nephrologic and metabolic, gastrointestinal, hematologic, infectious, endocrine, rheumatologic, and neuro-psychiatric. This evidence-based resource is ideal for educating clinicians delivering palliative care to cancer patients in acute care facilities about complex internal medicine problems, decision-making regarding diagnostics and therapeutics which require a good understanding of state-of-the-art internal medicine and palliative care principles.

The Oxford American Handbook of Hospice and Palliative Medicine and Supportive Care is an easily-navigable source of information about the day-to-day management of patients requiring palliative and hospice care. The table of contents follows the core curriculum of the American Board of Hospice and Palliative Medicine, thus meeting the educational and clinical information needs of students, residents, fellows, and nurse practitioners. Succinct, evidence-based, topically-focused content is supplemented by extensive tables, algorithms, and clinical pearls. This edition includes new sections on grief and bereavement, medical marijuana, and physician assisted suicide, and has been updated throughout to incorporate National Consensus Project for Quality Palliative Care Clinical Practice Guidelines.

Nutrition, appetite, and involuntary weight loss are issues that affect a large number of cancer patients and cancer survivors. Aspects such as symptom management, behavioural modification, exercise and medication are all important aspects of cancer care, but nutritional issues at the end of life can be accompanied by contentious ethical factors as well as religious and cultural influences that need to be addressed by health professionals. This book enables physicians, nurses and also dieticians to better discuss these complex issues with patients and their families.This comprehensive reference book provides both background information and practical, clinical advice for managing the cancer patient at all stages of their disease trajectory. It includes information that relates to patients who are continuing to receive disease-specific therapy, the cancer survivor, as well as patients with advanced or recurrent cancer receiving palliative care. Basic principles such as epidemiology and physiology set the scene, leading into the cachexia/anorexia syndrome, treatment options, nutritional counselling, enteral and parenteral nutrition, complementary/alternative therapies, exercise, clinical outcomes measures in each of the clinical groups, and focus on special populations and their specific needs. Multidimensional, interdisciplinary clinical evaluation and treatment is emphasised, and ethical, religious, and cultural factors are also addressed.Multidisciplinary in nature, this book draws on the experience of the editors' work across the fields of oncology, palliative care, surgery, primary care, nursing, dietetics and nutritional science. It will prove invaluable to all general practitioners, internists, medical oncologists and surgeons, nurses, palliative care specialists and related professionals involved in the care of the cancer patient.

This new edition provides the essential clinical guidance both for those embarking upon a career in palliative medicine and for those already established in the field. A team of international experts here distil what every practitioner needs to know into a practical and reliable resource.

Patients with advanced cancer increasingly receive end-of-life care from a variety of health care professionals, physicians and nurses. These professionals need to be able to assess the original diagnosis and the appropriateness of patient referral, set a treatment or palliation program, and recognise and plan for the clinical problems associated with specific primary tumors. This is the first comprehensive source of information available at a level between specialist oncology texts and nursing texts. Two eminent physicians from one of the world's foremost cancer centers have drawn together a remarkable team to provide a handbook which covers the full range of problems the healthcare workforce caring for these patients will encounter. This highly accessible text covers general principles in oncology, the primary tumors one by one, and management of specific symptoms and syndromes. It will be invaluable to primary care physicians, surgeons, nurses, therapists and trainees.