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2 produkter
3 784 kr
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Thanks to recent advancements, optimization is now recognized as a crucial component in research and decision-making across a number of fields. Through optimization, scientists have made tremendous advances in cancer treatment planning, disease control, and drug development, as well as in sequencing DNA, and identifying protein structures.Optimization in Medicine and Biology provides researchers with a comprehensive, single-source reference that will enable them to apply the very latest optimization techniques to their work. With contributions from pioneering international experts this volume integrates strong foundational theory, good modeling techniques, and efficient and robust algorithms with relevant applications Divided into two sections, the first begins with mathematical programming techniques for medical decision making processes and demonstrates their application to optimizing pediatric vaccine formularies, kidney paired donation, and the cost-effectiveness of HIV programs. It also presents recent advances in cancer treatment planning models and solution algorithms, including three-dimensional conventional conformal radiation therapy (3DCRT), intensity modulated radiation therapy (IMRT), tomotherapy, and proton therapy. Part two focuses on optimization in biology and discusses computational algorithms for genomic analysis; probe design and selection, properties of probes, and various algorithms and software packages to aid in probe selection and design. Subsequent chapters introduce a new dihedral angle measure for protein secondary prediction, and an optimization approach for tumor virotherapy with recombinant measles viruses. The editors include a short tutorial appendix on Integer Programming (IP). Highlighting the most recent advances in optimization techniques for solving complex problems in medical research, this book facilitates strong collaborative environments among optimization researchers and medical professionals for future medical research.
1 417 kr
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Features of statistical and operational research methods and tools being used to improve the healthcare industryWith a focus on cutting-edge approaches to the quickly growing field of healthcare, Healthcare Analytics: From Data to Knowledge to Healthcare Improvement provides an integrated and comprehensive treatment on recent research advancements in data-driven healthcare analytics in an effort to provide more personalized and smarter healthcare services. Emphasizing data and healthcare analytics from an operational management and statistical perspective, the book details how analytical methods and tools can be utilized to enhance healthcare quality and operational efficiency.Organized into two main sections, Part I features biomedical and health informatics and specifically addresses the analytics of genomic and proteomic data; physiological signals from patient-monitoring systems; data uncertainty in clinical laboratory tests; predictive modeling; disease modeling for sepsis; and the design of cyber infrastructures for early prediction of epidemic events. Part II focuses on healthcare delivery systems, including system advances for transforming clinic workflow and patient care; macro analysis of patient flow distribution; intensive care units; primary care; demand and resource allocation; mathematical models for predicting patient readmission and postoperative outcome; physician–patient interactions; insurance claims; and the role of social media in healthcare. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement also features:• Contributions from well-known international experts who shed light on new approaches in this growing area• Discussions on contemporary methods and techniques to address the handling of rich and large-scale healthcare data as well as the overall optimization of healthcare system operations• Numerous real-world examples and case studies that emphasize the vast potential of statistical and operational research tools and techniques to address the big data environment within the healthcare industry• Plentiful applications that showcase analytical methods and tools tailored for successful healthcare systems modeling and improvementThe book is an ideal reference for academics and practitioners in operations research, management science, applied mathematics, statistics, business, industrial and systems engineering, healthcare systems, and economics. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement is also appropriate for graduate-level courses typically offered within operations research, industrial engineering, business, and public health departments.