Eve K. Nichols – författare
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2 produkter
322 kr
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This is a landmark introduction to the facts and hopes of gene therapy: an exciting, albeit controversial, technique that could bring about a new age in medical treatment. Modern medicine has had relatively little to offer children with disorders such as thalassemia and severe combined immune deficiency. Many of these young patients still face repeated hospitalizations and, often, an early death. In gene therapy, a child with life-threatening genetic disease caused by a defect in a single gene will he treated with the gene’s normal counterpart. Successful development of somatic cell gene therapy is potentially the most effective new therapeutic approach to helping these children lead normal lives.With unusual clarity of style, Eve K. Nichols (author of the acclaimed Mobilizing Against AIDS) explores the potential for gene therapy and identifies those who are candidates for it. She reviews methods for diagnosing genetic diseases and evaluates current forms of therapy. Having provided a biomedical background for understanding somatic cell gene therapy, Nichols takes a thoughtful look at complex and sensitive issues surrounding ethical, economic, and policy aspects of manipulating human genes. A straightforward analysis of the current limitations and future potential of gene therapy concludes her broadly accessible account.This book is is derived from the annual session of the prestigious Institute of Medicine. Distinguished participants in this meeting, such as Leon Rosenberg (Dean of the Yale Medical School), Philip Leder (Harvard Medical School), David Martin (Vice President, Genentech, Inc.), James Wyngaarden (Director of the National Institutes of Health), and LeRoy Walters (Director of the Center for Bioethics, Georgetown University), have contributed expert perspectives that will establish this book as a standard of excellence for future studies. A preface by Frank Press, President of the National Academy of Sciences, provides an insightful overview of this promising new therapy.
309 kr
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The most important public health problem of our time—AIDS—is also the most shrouded in myth and misinformation. To bring the facts out of the shadows of fear and hysteria, the first edition of Mobilizing against AIDS was published in 1986. This new edition, nearly double the size of the first, interprets the results of the latest research on the disease and possible methods of treatment.For the foreseeable future the vast majority of AIDS cases will occur among groups that have already experienced major losses: homosexual and bisexual men, intravenous drug abusers, people who received blood or blood products before techniques were developed to safeguard the blood supply, heterosexual partners of those at recognized risk of HIV infection, and infants born to infected mothers. Mobilizing against AIDS examines new data on the growth of the epidemic within these groups, as well as on successful and failed attempts to stop the spread of the disease. In addition, it explores the growing problem of AIDS among the urban poor.This new edition also presents up to date information on how the disease affects the body, including damage to immune cells, bone marrow cells, skin cells, and cells of the cervix and colon. It contains additional discussions of treatment (particularly drug therapy and prospects for a vaccine) and a searching examination of the implications of societal and individual stress caused by the epidemic. In summarizing the events that have taken place in the last few years, Eve K. Nichols has worked closely with the Institute of Medicine, National Academy of Sciences and other key players in the battle against AIDS. Maintaining the clear and nontechnical style that has been so widely acclaimed, Nichols has forged an extraordinarily thorough synthesis that carries an authoritative stamp, ensuring that this new edition will be an indispensable resource for everyone concerned with AIDS and its treatment.