Francis S. Collins - Böcker

"Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such an effort, but also that its scientific worth would prove too modest to warrant the investment of human and financial capital that the project would require. This collection of essays stands as eloquent testimony to those who overcame such doubts to create, nurture, and finish the sequencing of the human genome in April 2003, a date that will forever stand out in human history. The wide and public availability of the human genome sequence and the other tools spawned by the Human Genome Project have helped to create an unparalleled era of biomedical discovery. It has opened up new avenues for the understanding of the biology of human health and disease. Many of these avenues remain to be fully explored, but this volume already demonstrates that information about genetics and genomics is increasingly permeating our clinical approach to patients."-from the Foreword by Dr. Elias Zerhouni For more than a century, knowledge about the role of genes has been gradually reshaping perceptions of our health and of ourselves.From Mendel's work with plants and Watson and Crick's model of DNA's double-helix structure to the recent decoding of the human genome, the tremendous advances in our ability to analyze and interpret gene sequences are revolutionizing many aspects of medicine. Genomic Medicine collects and updates an acclaimed series of articles published in the pages of the New England Journal of Medicine since November 2002 that together provide an authoritative and comprehensive overview of the latest developments in the field of medical genetics and an exploration of where these advances might take medicine over the next decade. Beginning with a fundamental primer and a useful glossary of terms, the book offers the latest information on the use of genetics to screen, diagnose, and treat a wide variety of diseases, including breast and ovarian cancer and cardiovascular, Alzheimer, and Parkinson disease. Also included are discussions of population screening, pharmacogenetics, and the ethical, legal, and social dimensions of genomic medicine.Edited by leaders in the field, written by experts from around the globe, and brimming with full-color illustrations, Genomic Medicine is an indispensable guide to the full potential of the DNA-based transformation of medicine.

'Inspirational'- YO YO MA'When Dr Collins speaks, I listen - and his message is more important now than ever'- PRESIDENT BILL CLINTON'Collins's personal journey of reflection and discovery will speak to many struggling to make sense of life, cope with uncertainty, and find their place in a greater scheme of things'- ALISTER MCGRATH'Francis is a careful, friendly and generous thinker. This book will help anyone who wishes to see integrity, civility and truth prevail in the public square.'- JUSTIN BRIERLEY'Dr Francis Collins is a bridge person in a polarized time. Amid the shrillness of our era, Collins offers a calming voice of hope'- PHILIP YANCEY'I would recommend this book to anyone.'- NICKY GUMBEL'This practical, refreshingly humble book offers guidance for all those worried about the state of wisdom in our world'- ELIZABETH OLDFIELDFrom world-leading scientist and New York Times bestselling author of The Language of God, a deeply thoughtful guidebook to discerning what and who we can trust to move us from societal discord to civic harmony.As the COVID-19 pandemic revealed, western society has become not just hyper-partisan, but also deeply cynical; distrustful of traditional sources of knowledge and wisdom such as science and faith. Scepticism about vaccines led to the needless deaths of at least 230,000 Americans, and "Do your own research" is now a rallying cry in many online rabbit holes. Yes, experts can make mistakes, and institutions can lose their moral compass, but there are reliable ways and means to weigh information and navigate truth, and The Road to Wisdom is here to help us rediscover them.Francis Collins reminds us of the four core sources of judgement and clear thinking: truth, science, faith, and trust. Drawing on his scientific work at the forefront of the Human Genome Project and the US National Institutes of Health, as well as on ethics, philosophy, and theology, Collins makes a robust, thoughtful case for each of these sources - their reliability, and their limits. Ultimately, he shows how they work together, not separately - and certainly not in conflict. It is only when we re-link these four pillars of wisdom that we can begin to discern the best path forward in life.​Hopeful, accessible, winsome, and deeply wise, The Road to Wisdom leads us beyond current animosities to surer footing. Here is the moral, philosophical, and scientific framework with which to address the problems of our time - on the world stage, but also in our daily lives.

'Dr Francis Collins is a bridge person in a polarized time. Amid the shrillness of our era, Collins offers a calming voice of hope, as well as practical suggestions on how to heal the nation's wounds.' - PHILIP YANCEYFrom world-leading scientist and New York Times bestselling author of The Language of God, a deeply thoughtful guidebook to discerning what and who we can trust to move us from societal discord to civic harmony.As the COVID-19 pandemic revealed, western society has become not just hyper-partisan, but also deeply cynical; distrustful of traditional sources of knowledge and wisdom such as science and faith. Scepticism about vaccines led to the needless deaths of at least 230,000 Americans, and "Do your own research" is now a rallying cry in many online rabbit holes. Yes, experts can make mistakes, and institutions can lose their moral compass, but there are reliable ways and means to weigh information and navigate truth, and The Road to Wisdom is here to help us rediscover them.Francis Collins reminds us of the four core sources of judgement and clear thinking: truth, science, faith, and trust. Drawing on his scientific work at the forefront of the Human Genome Project and the US National Institutes of Health, as well as on ethics, philosophy, and theology, Collins makes a robust, thoughtful case for each of these sources - their reliability, and their limits. Ultimately, he shows how they work together, not separately - and certainly not in conflict. It is only when we re-link these four pillars of wisdom that we can begin to discern the best path forward in life.​Hopeful, accessible, winsome, and deeply wise, The Road to Wisdom leads us beyond current animosities to surer footing. Here is the moral, philosophical, and scientific framework with which to address the problems of our time - on the world stage, but also in our daily lives.

From world-leading scientist and New York Times bestselling author of The Language of God, a deeply thoughtful guidebook to discerning what and who we can trust to move us from societal discord to civic harmony.As the COVID-19 pandemic revealed, western society has become not just hyper-partisan, but also deeply cynical; distrustful of traditional sources of knowledge and wisdom such as science and faith. Scepticism about vaccines led to the needless deaths of at least 230,000 Americans, and "Do your own research" is now a rallying cry in many online rabbit holes. Yes, experts can make mistakes, and institutions can lose their moral compass, but there are reliable ways and means to weigh information and navigate truth, and The Road to Wisdom is here to help us rediscover them.Francis Collins reminds us of the four core sources of judgement and clear thinking: truth, science, faith, and trust. Drawing on his scientific work at the forefront of the Human Genome Project and the US National Institutes of Health, as well as on ethics, philosophy, and theology, Collins makes a robust, thoughtful case for each of these sources - their reliability, and their limits. Ultimately, he shows how they work together, not separately - and certainly not in conflict. It is only when we re-link these four pillars of wisdom that we can begin to discern the best path forward in life.​Hopeful, accessible, winsome, and deeply wise, The Road to Wisdom leads us beyond current animosities to surer footing. Here is the moral, philosophical, and scientific framework with which to address the problems of our time - on the world stage, but also in our daily lives.